Flestolol

Base Information

Chemical Name:Flestolol
CAS No.:87721-62-8
Molecular Formula:C₁₅H₂₂FN₃O₄
Molecular Weight:327.356
Hs Code.:
UNII:LI02075E1W,39WX8P569M,V8FW2XAC43
DSSTox Substance ID:DTXSID60868981
Nikkaji Number:J128.615C
Wikipedia:Flestolol
Wikidata:Q15634013
NCI Thesaurus Code:C72784
ChEMBL ID:CHEMBL7467
Mol file:87721-62-8.mol

Synonyms:ACC 9089;ACC-9089;flestolol;flestolol sulfate

Suppliers and Price of Flestolol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Flestolol
100mg
$ 1010.00

American Custom Chemicals Corporation
FLESTOLOL 95.00%
5MG
$ 498.44

Total 7 raw suppliers

Chemical Property of Flestolol

Chemical Property:

Vapor Pressure:1.81E-10mmHg at 25°C
Boiling Point:491.3°Cat760mmHg
Flash Point:250.9°C
PSA：113.68000
Density:1.242g/cm³
LogP:1.86200
XLogP3:0.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:327.15943435
Heavy Atom Count:23
Complexity:406

Purity/Quality:

99% ^*data from raw suppliers

Flestolol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(CNC(=O)N)NCC(COC(=O)C1=CC=CC=C1F)O
Uses Flestolol is?a nonselective, competitive, ultra-short-acting beta-adrenergic?antagonist. It is?metabolized by plasma esterases with an elimination half-life of approximately 6.5 minutes.

Technology Process of Flestolol

There total 3 articles about Flestolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 393-52-2
2-Fluorobenzoyl chloride

: 87721-62-8,100511-22-6
3-<<1,1-dimethyl-2-<(aminocarbonyl)amino>ethyl>amino>-2-hydroxypropyl 2-fluorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 96.2 percent / Et₃N / diethyl ether / 2 h / Ambient temperature

2: dimethylformamide / 6 h / 65 °C

With triethylamine; In diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jm00374a013