(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylic acid

Base Information

Chemical Name:(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylic acid
CAS No.:176439-44-4
Molecular Formula:C12H14N2O3
Molecular Weight:234.25
Hs Code.:
DSSTox Substance ID:DTXSID30570983
Nikkaji Number:J714.170J
Mol file:176439-44-4.mol

Synonyms:176439-44-4;(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylic acid;(2S,4S)-4-AMINO-1-BENZOYL-PYRROLIDINE-2-CARBOXYLIC ACID;(4S)-4-amino-1-benzoyl-L-Proline;(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylicacid;SCHEMBL16556134;DTXSID30570983;AKOS015854144;AKOS015898289;BS-41650;CS-0333828;W18886;A812185;J-501051;(2S,4S)-4-amino-1-benzoyl-pyrrolidine-2-carboxylic acid, AldrichCPR

Suppliers and Price of (2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylicacid 95+%
250mg
$ 410.00

Crysdot
(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylicacid 95+%
1g
$ 1027.00

Chemenu
(2S,4S)-4-AMINO-1-BENZOYL-PYRROLIDINE-2-CARBOXYLICACID 95%
1g
$ 968.00

American Custom Chemicals Corporation
(2S,4S)-4-AMINO-1-BENZOYL-PYRROLIDINE-2-CARBOXYLIC ACID 95.00%
1G
$ 2054.85

American Custom Chemicals Corporation
(2S,4S)-4-AMINO-1-BENZOYL-PYRROLIDINE-2-CARBOXYLIC ACID 95.00%
0.5G
$ 1314.50

Alichem
(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylicacid
1g
$ 848.64

Alichem
(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylicacid
250mg
$ 430.56

Total 17 raw suppliers

Chemical Property of (2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:462.666°C at 760 mmHg
Flash Point:233.612°C
PSA：83.63000
Density:1.326g/cm³
LogP:0.95120
Storage Temp.:Store at 0-5°C
XLogP3:-2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:234.10044231
Heavy Atom Count:17
Complexity:313

Purity/Quality:

97% ^*data from raw suppliers

(2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CN(C1C(=O)O)C(=O)C2=CC=CC=C2)N
Isomeric SMILES:C1[C@@H](CN([C@@H]1C(=O)O)C(=O)C2=CC=CC=C2)N

Technology Process of (2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylic acid

There total 6 articles about (2S,4S)-4-Amino-1-benzoylpyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: (2S,4S)-4-Azido-1-benzoyl-pyrrolidine-2-carboxylic acid

: 176439-44-4
N-α-benzoyl-cis-4-amino-L-proline

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1016/0040-4039(96)00307-3

Reference yield:

: 1499-56-5,775275-31-5,790644-51-8,754962-86-2
(R)-4-hydroxy-L-proline ethyl ester

: 176439-44-4
N-α-benzoyl-cis-4-amino-L-proline

Guidance literature:: Multi-step reaction with 5 steps

1: NaHCO₃ / dioxane; H₂O

2: 77 percent / pyridine

3: 96 percent / NaN₃ / dimethylformamide / 60 °C

4: 87 percent / aq. LiOH / tetrahydrofuran

5: 100 percent / H₂ / Pd-C / methanol

With pyridine; lithium hydroxide; sodium azide; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(96)00307-3

Reference yield:

: 31560-20-0,120806-96-4
(2S,4R)-1-benzoyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester

: 176439-44-4
N-α-benzoyl-cis-4-amino-L-proline

Guidance literature:: Multi-step reaction with 4 steps

1: 77 percent / pyridine

2: 96 percent / NaN₃ / dimethylformamide / 60 °C

3: 87 percent / aq. LiOH / tetrahydrofuran

4: 100 percent / H₂ / Pd-C / methanol

With pyridine; lithium hydroxide; sodium azide; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(96)00307-3