2-(trifluoroMethyl)-6,7-dihydro-5Hpyrrolo[3,4-b]pyridine

Base Information

• Chemical Name: 2-(trifluoroMethyl)-6,7-dihydro-5Hpyrrolo[3,4-b]pyridine
• CAS No.: 905273-59-8
• Molecular Formula: C8H7F3N2
• Molecular Weight: 188.15
• Hs Code.: 2933990090
• Mol file: 905273-59-8.mol

Synonyms:2-(trifluoromethyl)-6,7-dihydro-5Hpyrrolo[3,4-b]pyridine;

Chemical Property of 2-(trifluoroMethyl)-6,7-dihydro-5Hpyrrolo[3,4-b]pyridine

Chemical Property:

• PSA: 24.92000
• LogP: 2.03240
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

2-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(trifluoroMethyl)-6,7-dihydro-5Hpyrrolo[3,4-b]pyridine

There total 1 articles about 2-(trifluoroMethyl)-6,7-dihydro-5Hpyrrolo[3,4-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C27H21F3N2 (905273-58-7) → C8H7F3N2 (905273-59-8)

Guidance literature:

With trifluoroacetic acid; In methanol; chloroform; at 20 ℃;

DOI:10.1016/j.bmcl.2010.09.124

Reference yield:

5-methane-sulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-benzoic acid (845616-82-2,845616-83-3) + C8H7F3N2 (905273-59-8) → [5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-(2-trifluoromethyl-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-methanone

Guidance literature:

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmcl.2010.09.124

upstream raw materials:

C₂₇H₂₁F₃N₂

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