1-Methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene

Base Information

Chemical Name:1-Methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene
CAS No.:174627-50-0
Molecular Formula:C26H40O2
Molecular Weight:384.602
Hs Code.:
DSSTox Substance ID:DTXSID90432699
Mol file:174627-50-0.mol

Synonyms:1-Methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene;SCHEMBL3688362;DTXSID90432699;BJIIKHXAZBTGLF-UHFFFAOYSA-N;J-011020

Suppliers and Price of 1-Methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
L-759,633 >98%
25mg
$ 420.00

Cayman Chemical
L-759,633 >98%
10mg
$ 192.00

Cayman Chemical
L-759,633 >98%
5mg
$ 108.00

Cayman Chemical
L-759,633 >98%
1mg
$ 24.00

American Custom Chemicals Corporation
L-759633 95.00%
25MG
$ 949.59

American Custom Chemicals Corporation
L-759633 95.00%
5MG
$ 680.99

American Custom Chemicals Corporation
L-759633 95.00%
1MG
$ 568.79

Total 16 raw suppliers

Chemical Property of 1-Methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene

Chemical Property:

Boiling Point:447.895 °C at 760 mmHg
Flash Point:134.245 °C
PSA：18.46000
Density:0.956 g/cm³
LogP:7.55410
Storage Temp.:Store at +4°C
XLogP3:8.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:384.302830514
Heavy Atom Count:28
Complexity:535

Purity/Quality:

99% ^*data from raw suppliers

L-759,633 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCC(C)(C)C1=CC2=C(C3CC(=C)CCC3C(O2)(C)C)C(=C1)OC
Description L-759,633 is a high-affinity peripheral cannabinoid receptor (CB2)-selective agonist with Ki values of 6.4 and 1,043 nM for CB2 and central cannabinoid (CB1) receptors, respectively. L-759,633 inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB2 or CB1 receptors with IC50 values of 8.1 nM and 10 μM, respectively.

Technology Process of 1-Methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene

There total 1 articles about 1-Methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 77-78-1
dimethyl sulfate

: (6aR,10aR)-3-(1,1-Dimethyl-heptyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol

: 174627-50-0
L 759633

Guidance literature:: With potassium carbonate; In acetone; Heating;
DOI:10.1016/S0968-0896(99)00219-9

Reference yield: 66.0%

: 174627-50-0
L 759633

: 137945-58-5
3-(1',1'-dimethylheptyl)-1-methoxy-11-oxo-Δ8-THC

Guidance literature:: With selenium(IV) oxide; In ethanol; Heating;
DOI:10.1016/S0968-0896(02)00331-0

Reference yield:

: 174627-50-0
L 759633

: 137945-55-2
11-hydroxy-3-(1',1'-dimethylheptyl)-1-methoxy-Δ8-THC

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / SeO₂ / ethanol / Heating

2: 93 percent / CeCl₃*7H₂O; NaBH₄; aq. HCl / methanol / 20 °C / pH 7.0

With hydrogenchloride; sodium tetrahydroborate; selenium(IV) oxide; cerium(III) chloride; In methanol; ethanol; 2: Luche reduction;
DOI:10.1016/S0968-0896(02)00331-0