3-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE

Base Information

• Chemical Name: 3-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE
• CAS No.: 945262-32-8
• Molecular Formula: C₈H₁₂N₄
• Molecular Weight: 164.21
• Hs Code.: 2933990090
• Mol file: 945262-32-8.mol

Synonyms:3-Cyclopropyl-5,6,7,8-tet...;3-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE;

Chemical Property of 3-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE

Chemical Property:

• Vapor Pressure: 4.81E-06mmHg at 25°C
• Boiling Point: 382.2°C at 760 mmHg
• Flash Point: 184.9°C
• PSA: 42.74000
• Density: 1.63g/cm³
• LogP: 0.58750
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

3-Cyclopropyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE

There total 2 articles about 3-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C8H8N4 → 3-cyclopropyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine (945262-32-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 18h;

DOI:10.1016/j.bmcl.2007.03.098

Reference yield:

C8H10N4O (945262-34-0) → 3-cyclopropyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine (945262-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: polyphosphoric acid / 18 h / 150 °C

2: H₂ / Pd/C / ethanol / 18 h / 20 °C

With PPA; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/j.bmcl.2007.03.098

upstream raw materials:

C₈H₁₀N₄O

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