(3R,5S)-rel-4-(Chlorocarbonyl)-3,5-dimethyl-1-piperazinecarboxylic acid tert-butyl ester

Base Information

Chemical Name:(3R,5S)-rel-4-(Chlorocarbonyl)-3,5-dimethyl-1-piperazinecarboxylic acid tert-butyl ester
CAS No.:438050-53-4
Molecular Formula:C12H21ClN2O3
Molecular Weight:276.76
Hs Code.:
Mol file:438050-53-4.mol

Synonyms:4-tert-butoxycarbonyl-1-chlorocarbonyl-2,6-diMethylpiperazine;(3S,5R)-tert-butyl 4-(chlorocarbonyl)-3,5-diMethylpiperazine-1-c;(3S,5R)-tert-butyl 4-(chlorocarbonyl)-3,5-dimethylpiperazine-1-carboxylate;(3R,5S)-rel-4-(Chlorocarbonyl)-3,5-dimethyl-1-piperazinecarboxylic acid tert-butyl ester;1-Piperazinecarboxylic acid, 4-(chlorocarbonyl)-3,5-dimethyl-, 1,1-dimethylethyl ester, (3R,5S)-rel-

Suppliers and Price of (3R,5S)-rel-4-(Chlorocarbonyl)-3,5-dimethyl-1-piperazinecarboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 6 raw suppliers

Chemical Property of (3R,5S)-rel-4-(Chlorocarbonyl)-3,5-dimethyl-1-piperazinecarboxylic acid tert-butyl ester

Chemical Property:

Boiling Point:368.1±31.0 °C(Predicted)
PKA:-0.33±0.70(Predicted)
Density:1.14

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of (3R,5S)-rel-4-(Chlorocarbonyl)-3,5-dimethyl-1-piperazinecarboxylic acid tert-butyl ester

There total 1 articles about (3R,5S)-rel-4-(Chlorocarbonyl)-3,5-dimethyl-1-piperazinecarboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 32315-10-9
bis(trichloromethyl) carbonate

: 129779-30-2,1152111-14-2
(3S,5R)-3,5-dimethylpiperazine-1-carboxylic acid tert-butyl ester

: 438050-53-4
tert-butyl (3R,5S)-4-(carbonochloridoyl)-3.5-dimethylpiperazine-1-carboxylate

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;

Reference yield:

: 438050-53-4
tert-butyl (3R,5S)-4-(carbonochloridoyl)-3.5-dimethylpiperazine-1-carboxylate

: 2-benzyl-2-azaspiro[3.3]heptan-6-ol

: 1-{2-benzyl-2-azaspiro[3.3]heptan-6-yl} 4-tert-butyl (2R,6S)-2.6-dimethylpiperazine-1,4-dicarboxylate

Guidance literature:: 2-benzyl-2-azaspiro[3.3]heptan-6-ol; With potassium hexamethylsilazane; In tetrahydrofuran; at 20 ℃; for 0.25h; Inert atmosphere;

tert-butyl (3R,5S)-4-(carbonochloridoyl)-3.5-dimethylpiperazine-1-carboxylate; In tetrahydrofuran; acetonitrile; at 50 ℃;