4-(Pyrrolidin-1-YL)benzene-1-sulfonyl chloride

Base Information

Chemical Name:4-(Pyrrolidin-1-YL)benzene-1-sulfonyl chloride
CAS No.:125393-18-2
Molecular Formula:C₁₀H₁₂ClNO₂S
Molecular Weight:245.73
Hs Code.:
DSSTox Substance ID:DTXSID30696915
Wikidata:Q82626679
Mol file:125393-18-2.mol

Synonyms:125393-18-2;4-pyrrolidin-1-ylbenzenesulfonyl chloride;4-(PYRROLIDIN-1-YL)BENZENE-1-SULFONYL CHLORIDE;4-Pyrrolidin-1-yl-benzenesulfonyl chloride;losefamicacid;SCHEMBL3176219;DTXSID30696915;RUMNUSUMGZRQBF-UHFFFAOYSA-N;MFCD12402753;AKOS006334835;BB 0239123;4-(pyrrolidin-1-yl) benzene-1-sulfonyl chloride;EN300-1987088

Suppliers and Price of 4-(Pyrrolidin-1-YL)benzene-1-sulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 7 raw suppliers

Chemical Property of 4-(Pyrrolidin-1-YL)benzene-1-sulfonyl chloride

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:245.0277275
Heavy Atom Count:15
Complexity:298

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C2=CC=C(C=C2)S(=O)(=O)Cl

Technology Process of 4-(Pyrrolidin-1-YL)benzene-1-sulfonyl chloride

There total 2 articles about 4-(Pyrrolidin-1-YL)benzene-1-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 853789-34-1
4-(1-pyrrolidyl)benzenesulfonic acid

: 125393-18-2
4-(1-pyrrolidyl)benzenesulfonyl chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 4096-21-3
N-phenylpyrrolidine

: 125393-18-2
4-(1-pyrrolidyl)benzenesulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: SO₃, dioxane / 1,2-dichloro-ethane / 1 h / Heating

2: POCl₃, 98 percent PCl₅ / CH₂Cl₂ / 4 h / Ambient temperature

With 1,4-dioxane; phosphorus pentachloride; sulfur trioxide; trichlorophosphate; In dichloromethane; 1,2-dichloro-ethane;