3-METHOXY-5-METHYLBENZONITRILE

Base Information

• Chemical Name: 3-METHOXY-5-METHYLBENZONITRILE
• CAS No.: 473923-98-7
• Molecular Formula: C9 H9 N O
• Molecular Weight: 147.177
• Hs Code.: 2926909090
• Mol file: 473923-98-7.mol

Synonyms:3-Methoxy-5-methylbenzonitrile

Chemical Property of 3-METHOXY-5-METHYLBENZONITRILE

Chemical Property:

• PSA: 33.02000
• LogP: 1.87528

Purity/Quality:

97% ^*data from raw suppliers

3-Methoxy-5-methylbenzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 3-METHOXY-5-METHYLBENZONITRILE

There total 6 articles about 3-METHOXY-5-METHYLBENZONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-bromo-5-methoxytoluene (29578-83-4) + dicyanozinc (557-21-1) → 3-methoxy-5-methylbenzonitrile (473923-98-7)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 90 ℃; for 7h;

Reference yield: 66.0%

3-bromo-5-methoxytoluene (29578-83-4) → 3-methoxy-5-methylbenzonitrile (473923-98-7)

Guidance literature:

With copper(I) cyanide; In DMF (N,N-dimethyl-formamide); at 60 ℃; for 20h;

Reference yield: 41.0%

zinc(II) cyanide (557-21-1) + 2-(3-methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (365564-09-6) → 3-methoxy-5-methylbenzonitrile (473923-98-7)

Guidance literature:

With copper(II) nitrate trihydrate; cesium fluoride; In methanol; water; at 100 ℃; Sealed vessel;

upstream raw materials:

3-bromo-5-methoxytoluene

dicyanozinc

zinc(II) cyanide

2-(3-methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Downstream raw materials:

1-(2,6-diisopropylphenyl)-2-(3-methoxy-5-methylphenyl)-1H-imidazole

3-(1-(2,6-diisopropylphenyl)-1H-imidazol-2-yl)-5-methylphenol

1-(2,6-diisopropylphenyl)-2-(3-(3-(1-(2,6-diisopropylphenyl)-1H-imidazol-2-yl)-5-methylphenoxy)phenyl)-1H-imidazole

2,2'-(oxybis(3-methyl-5,1-phenylene))bis(1-(2,6-diisopropylphenyl)-1H-imidazole)