TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL

Base Information

• Chemical Name: TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL
• CAS No.: 84892-42-2
• Molecular Formula: C₁₂H₁₅BrO
• Molecular Weight: 255.155
• Mol file: 84892-42-2.mol

Synonyms:TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL

Chemical Property of TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL

Chemical Property:

• PSA: 20.23000
• Density: 1.388±0.06 g/cm3 (20 ºC 760 Torr)
• LogP: 3.46760

Purity/Quality:

98%,99%, ^*data from raw suppliers

trans-4-(4-Bromophenyl)cyclohexan-1-ol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL

There total 15 articles about TRANS-4-(4-BROMOPHENYL)CYCLOHEXANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ cis-4-(4-bromophenyl)cyclohexanol (84892-42-2)

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; hydrogen; C₄₅H₃₈FeNO₂P; lithium tert-butoxide; In ethanol; isopropyl alcohol; at 20 ℃; for 12h; under 3750.38 Torr; Inert atmosphere; Glovebox;

Reference yield:

(cis)-4-(4-bromophenyl)cyclohexyl 2-fluorobenzoate → (cis)-4-(4-bromophenyl)cyclohexanol (84892-42-2)

Guidance literature:

With water; sodium hydroxide; In methanol; at 20 - 40 ℃; for 53h;

Reference yield:

(trans)-4-phenylcyclohexanol → (trans)-4-(4-bromophenyl)cyclohexanol (84892-42-2)

Guidance literature:

(trans)-4-phenylcyclohexanol; With aluminum (III) chloride; In dichloromethane; at -8 ℃; for 0.25h;

With bromine; In dichloromethane; for 0.166667h;

upstream raw materials:

1-phenyl-4-cyclohexanone

trans-4-phenylcyclohexanol

Refernces

• 1、 -. "GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE". . . Retrieved 2021/01/22.
• 2、 -. "AZABENZIMIDAZOLE DERIVATIVES". . . Retrieved 2015/05/19.