(Z)-methyl3-(2,4-dimethyl-5-((2-oxoindolin- 3-ylidene)methyl)-1H-pyrrol-3-yl)propanoate

Base Information

Chemical Name:(Z)-methyl3-(2,4-dimethyl-5-((2-oxoindolin- 3-ylidene)methyl)-1H-pyrrol-3-yl)propanoate
CAS No.:548740-24-5
Molecular Formula:C₁₉H₂₀N₂O₃
Molecular Weight:324.379
Hs Code.:
Mol file:548740-24-5.mol

Synonyms:(Z)-Methyl3-(2,4-diMethyl-5-((2-oxoindolin- 3-ylidene)Methyl)-1H-pyrrol-3-yl)propanoate;5-[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid methyl ester;1H-Pyrrole-3-propanoic acid, 5-[(Z)-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, methyl ester

Suppliers and Price of (Z)-methyl3-(2,4-dimethyl-5-((2-oxoindolin- 3-ylidene)methyl)-1H-pyrrol-3-yl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of (Z)-methyl3-(2,4-dimethyl-5-((2-oxoindolin- 3-ylidene)methyl)-1H-pyrrol-3-yl)propanoate

Chemical Property:

Melting Point:216-217℃ (dichloromethane methanol )
PSA：74.68000
LogP:3.31490

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (Z)-methyl3-(2,4-dimethyl-5-((2-oxoindolin- 3-ylidene)methyl)-1H-pyrrol-3-yl)propanoate

There total 2 articles about (Z)-methyl3-(2,4-dimethyl-5-((2-oxoindolin- 3-ylidene)methyl)-1H-pyrrol-3-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 59-48-3
2-oxoindole

: 18818-25-2
methyl 3-(5-formyl-2,4-dimethyl-1H-pyrrol-3-yl)propanoate

: 548740-24-5
(Z)-3-[(3,5-dimethyl-4-(2-methoxycarbonylethyl)-1H-pyrrol-2-yl)-methylidenyl]-indolin-2-one

Guidance literature:: With piperidine; In methanol; for 8h; Heating;
DOI:10.1002/jhet.5570400127

Reference yield:

: 16132-20-0
tert-butyl 3,5-dimethyl-4-(2-methoxycarbonylethyl)-1H-pyrrole-2-carboxylate

: 548740-24-5
(Z)-3-[(3,5-dimethyl-4-(2-methoxycarbonylethyl)-1H-pyrrol-2-yl)-methylidenyl]-indolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / CH₂Cl₂ / 0.33 h

1.2: 87 percent / triethylorthoformate / CH₂Cl₂ / 0.33 h / 4 °C

2.1: 79 percent / piperidine / methanol / 8 h / Heating

With piperidine; trifluoroacetic acid; In methanol; dichloromethane;
DOI:10.1002/jhet.5570400127