11BETA-PROSTAGLANDIN F1BETA

Base Information

Chemical Name:11BETA-PROSTAGLANDIN F1BETA
CAS No.:37785-86-7
Molecular Formula:C20H36O5
Molecular Weight:356.5
Hs Code.:
Mol file:37785-86-7.mol

Synonyms:9BETA,11BETA-PGF1ALPHA;9BETA,11BETA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID;

Suppliers and Price of 11BETA-PROSTAGLANDIN F1BETA

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
11β-Prostaglandin F1β ≥99%
1mg
$ 69.00

Cayman Chemical
11β-Prostaglandin F1β ≥99%
500μg
$ 50.00

American Custom Chemicals Corporation
11BETA-PROSTAGLANDIN F1BETA 95.00%
5MG
$ 504.68

AK Scientific
11beta-ProstaglandinF1beta
1mg
$ 185.00

Total 3 raw suppliers

Chemical Property of 11BETA-PROSTAGLANDIN F1BETA

Chemical Property:

PSA：97.99000
LogP:3.26690

Purity/Quality:

99% ^*data from raw suppliers

11β-Prostaglandin F1β ≥99% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 11BETA-PROSTAGLANDIN F1BETA

There total 39 articles about 11BETA-PROSTAGLANDIN F1BETA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 71120-99-5,71121-00-1,72120-47-9
2β-<(1E)-3-<(tert-butyldimethylsilyl)oxy>oct-1-enyl>-3α-(6-carboxyhexyl)-1α,4α-dihydroxycyclopentanone

: 745-62-0,3613-66-9,10164-73-5,17066-90-9,20348-60-1,21562-54-9,26771-95-9,26771-96-0,34388-84-6,34388-86-8,34388-87-9,34388-89-1,34402-61-4,34437-28-0,37785-86-7,37818-61-4,42048-97-5,42587-03-1,42607-55-6,42607-56-7,54422-22-9,54422-23-0,55528-78-4,57759-92-9,57759-93-0,61375-87-9,61557-40-2,62860-86-0,62960-89-8
(+/-)-prostaglandin F1α

Guidance literature:: With hydrogen fluoride; In water; acetonitrile; for 1h; Ambient temperature;
DOI:10.1021/jo00231a014

Reference yield:

: 78823-20-8
trans-4-<(1E)-3-<(tert-butyldimethylsilyl)oxy>oct-1-enyl>-2,3-epoxycyclopentanone

: 745-62-0,3613-66-9,10164-73-5,17066-90-9,20348-60-1,21562-54-9,26771-95-9,26771-96-0,34388-84-6,34388-86-8,34388-87-9,34388-89-1,34402-61-4,34437-28-0,37785-86-7,37818-61-4,42048-97-5,42587-03-1,42607-55-6,42607-56-7,54422-22-9,54422-23-0,55528-78-4,57759-92-9,57759-93-0,61375-87-9,61557-40-2,62860-86-0,62960-89-8
(+/-)-prostaglandin F1α

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) lithium diisopropylamide / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to r.t., 6 h

2: 1.) CuCN / 1.) diethyl ether, -40 deg C, 1.5 h, 2.) ether, from -78 deg C to -10 deg C, overnight

3: KF, pH 7 phosphate buffer / ethanol / 3 h / Ambient temperature

4: 84 percent / L-selectride / tetrahydrofuran / 6 h / Ambient temperature

5: 75 percent / O₂ / PtO₂ / acetone; H₂O / 4 h / 40 °C

6: 90 percent / 47-52percent aq. HF / acetonitrile; H₂O / 1 h / Ambient temperature

With potassium fluoride; pH 7 phosphate buffer; hydrogen fluoride; oxygen; L-Selectride; lithium diisopropyl amide; platinum(IV) oxide; In tetrahydrofuran; ethanol; water; acetone; acetonitrile;
DOI:10.1021/jo00231a014

Reference yield:

: 93566-56-4,93711-56-9,110548-21-5
trans-4,5-epoxy-3-<(1E)-3-<(tert-butyldimethylsilyl)oxy>oct-1-enyl>-1-<(triethylsilyl)oxy>cyclopentene

: 745-62-0,3613-66-9,10164-73-5,17066-90-9,20348-60-1,21562-54-9,26771-95-9,26771-96-0,34388-84-6,34388-86-8,34388-87-9,34388-89-1,34402-61-4,34437-28-0,37785-86-7,37818-61-4,42048-97-5,42587-03-1,42607-55-6,42607-56-7,54422-22-9,54422-23-0,55528-78-4,57759-92-9,57759-93-0,61375-87-9,61557-40-2,62860-86-0,62960-89-8
(+/-)-prostaglandin F1α

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) CuCN / 1.) diethyl ether, -40 deg C, 1.5 h, 2.) ether, from -78 deg C to -10 deg C, overnight

2: KF, pH 7 phosphate buffer / ethanol / 3 h / Ambient temperature

3: 84 percent / L-selectride / tetrahydrofuran / 6 h / Ambient temperature

4: 75 percent / O₂ / PtO₂ / acetone; H₂O / 4 h / 40 °C

5: 90 percent / 47-52percent aq. HF / acetonitrile; H₂O / 1 h / Ambient temperature

With potassium fluoride; pH 7 phosphate buffer; hydrogen fluoride; oxygen; L-Selectride; platinum(IV) oxide; In tetrahydrofuran; ethanol; water; acetone; acetonitrile;
DOI:10.1021/jo00231a014