Decarboxy Enrofloxacin

Base Information

• Chemical Name: Decarboxy Enrofloxacin
• CAS No.: 131775-99-0
• Molecular Formula: C18H22FN3O
• Molecular Weight: 315.39
• Mol file: 131775-99-0.mol

Synonyms:Decarboxy Enrofloxacin;1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4(1H)-quinolinone

Chemical Property of Decarboxy Enrofloxacin

Chemical Property:

• Melting Point: 157-158°C
• Boiling Point: 489.9±45.0 °C(Predicted)
• PKA: 7.76±0.10(Predicted)
• PSA: 28.48000
• Density: 1.266±0.06 g/cm3(Predicted)
• LogP: 2.62030
• Storage Temp.: Refrigerator
• Solubility.: Chloroform, Methanol

Purity/Quality:

97% ^*data from raw suppliers

Decarboxy enrofloxacin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Decarboxy Enrofloxacin (Enrofloxacin EP Impurity F) is an Enrofloxacin (E557800) impurity. Enrofloxacin (E557800) impurity.

Technology Process of Decarboxy Enrofloxacin

There total 1 articles about Decarboxy Enrofloxacin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

enrofloxacin (93106-60-6) → 7-(4-ethylpiperazin-1-yl)-1-cyclopropyl-6-fluoroquinolin-4-one (131775-99-0)

Guidance literature:

With potassium cyanide; In N,N-dimethyl-formamide; at 120 ℃; for 24h;

DOI:10.1016/j.bmcl.2011.07.060

upstream raw materials:

enrofloxacin

Refernces