SRT3109

Base Information

Chemical Name:SRT3109
CAS No.:1204707-71-0
Molecular Formula:C18H23F2N5O4S2
Molecular Weight:475.541
Hs Code.:
Mol file:1204707-71-0.mol

Synonyms:SRT3109;N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2R,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide;

Suppliers and Price of SRT3109

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1R,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide
5mg
$ 270.00

DC Chemicals
SRT-3109 >98%
1 g
$ 3600.00

DC Chemicals
SRT-3109 >98%
250 mg
$ 1700.00

DC Chemicals
SRT-3109 >98%
100 mg
$ 950.00

Crysdot
SRT3109 98+%
10mg
$ 496.00

Crysdot
SRT3109 98+%
5mg
$ 380.00

ChemScene
SRT3109 99.82%
5mg
$ 343.00

Biosynth Carbosynth
AZD 5069
50 mg
$ 507.50

Biosynth Carbosynth
AZD 5069
10 mg
$ 145.00

ApexBio Technology
SRT3109
5mg
$ 452.00

Total 17 raw suppliers

Chemical Property of SRT3109

Chemical Property:

PSA：161.36000
Density:1.55
LogP:2.72780

Purity/Quality:

99%, ^*data from raw suppliers

N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1R,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1R,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide is a CXCR2 ligand and a potent chemoattractants for neutrophils.

Technology Process of SRT3109

There total 2 articles about SRT3109 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1204707-81-2
N-[2-[(2,3-difluorobenzyl)thio]-6-({(1R)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethyl}amino)pyrimidin-4-yl]azetidine-1-sulfonamide

: 1204707-71-0
N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(1R,2R)-2,3-dihydroxy-1-methyl-propyl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide

Guidance literature:: With toluene-4-sulfonic acid; In methanol; water; at 60 ℃; for 20h; Product distribution / selectivity;

Reference yield: 63.0%

: 654073-32-2
1-azetidine-1-sulfonamide

: 1204707-78-7
(2R,3R)-3-({6-chloro-2-[(2,3-difluorobenzyl)thio]pyrimidin-4-yl}amino)butane-1,2-diol

: 1204707-71-0
N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(1R,2R)-2,3-dihydroxy-1-methyl-propyl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide

Guidance literature:: With caesium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; XPhos; In 1,4-dioxane; at 105 ℃; for 1.5h; Product distribution / selectivity; Inert atmosphere;