4-(p-tolyl)-4-dimethylaminocyclohexanone

Base Information

• Chemical Name: 4-(p-tolyl)-4-dimethylaminocyclohexanone
• CAS No.: 65619-06-9
• Molecular Formula: C15H21NO
• Molecular Weight: 231.33
• Hs Code.: 2922399090
• Mol file: 65619-06-9.mol

Synonyms:4-(dimethylamino)-4-p-tolyl-cyclohexanone;4-Dimethylamino-4-(p-tolyl)-cyclohexanon;4-(p-tolyl)-4-dimethylaminocyclohexanone;

Chemical Property of 4-(p-tolyl)-4-dimethylaminocyclohexanone

Chemical Property:

• PSA: 20.31000
• LogP: 2.89500

Purity/Quality:

98% ^*data from raw suppliers

4-(dimethylamino)-4-(p-tolyl)cyclohexan-1-one 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(p-tolyl)-4-dimethylaminocyclohexanone

There total 2 articles about 4-(p-tolyl)-4-dimethylaminocyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

4-dimethylamino-4-(p-tolyl)cyclohexanone, ethylene ketal hydrochloride (65619-05-8) → 4-(dimethylamino)-4-p-tolyl-cyclohexanone (65619-06-9)

Guidance literature:

With hydrogenchloride; In methanol; for 48h; Ambient temperature;

DOI:10.1021/jm00178a014

Reference yield: 55.0%

→ 4-(dimethylamino)-4-p-tolyl-cyclohexanone (65619-06-9)

Guidance literature:

Reference yield: 29.0%

4-(dimethylamino)-4-p-tolyl-cyclohexanone (65619-06-9) + acetylenemagnesium bromide (4301-14-8) → 4-Dimethylamino-1-ethynyl-4-p-tolyl-cyclohexanol (70894-79-0) + 4-Dimethylamino-1-ethynyl-4-p-tolyl-cyclohexanol (70894-80-3)

Guidance literature:

In tetrahydrofuran; for 40h; Ambient temperature;

DOI:10.1021/jm00136a010

upstream raw materials:

4-dimethylamino-4-(p-tolyl)cyclohexanone, ethylene ketal hydrochloride

Downstream raw materials:

4-Dimethylamino-1-methyl-4-p-tolyl-cyclohexanol

4-Dimethylamino-1-methyl-4-p-tolyl-cyclohexanol

4-Dimethylamino-1-ethynyl-4-p-tolyl-cyclohexanol

4-Dimethylamino-1-ethynyl-4-p-tolyl-cyclohexanol

Refernces

• 1、 -. "4-Amino-4-phenylcyclohexanone ketal compositions and process of use". . . Retrieved 2008/06/13.