N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester

Base Information

Chemical Name:N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester
CAS No.:1093865-09-8
Molecular Formula:C14H28N2O3
Molecular Weight:272.39
Hs Code.:2932999099
Mol file:1093865-09-8.mol

Synonyms:N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester

Suppliers and Price of N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 7 raw suppliers

Chemical Property of N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester

Chemical Property:

Boiling Point:370℃
Flash Point:178℃
PSA：64.79000
Density:1.026
LogP:2.69760

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester

There total 2 articles about N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1093865-07-6
1,1-dimethylethyl methyl{(1R)-2-({[(phenylmethyl)oxy]carbonyl}amino)-1-[(3S)-tetrahydro-2H-pyran-3-ylmethyl]ethyl}carbamate

: 1093865-09-8
1,1-dimethylethyl {(1R)-2-amino-1-[(3S)-tetrahydro-2H-pyran-3-ylmethyl]ethyl}methylcarbamate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 2h;

Reference yield:

: 1093865-87-2
1,1-dimethylethyl methyl{2-({[(phenylmethyl)oxy]carbonyl}amino)-1-[(3S)-tetrahydro-2H-pyran-3-ylmethyl]ethyl}carbamate

: 1093865-09-8
1,1-dimethylethyl {(1R)-2-amino-1-[(3S)-tetrahydro-2H-pyran-3-ylmethyl]ethyl}methylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: hexane; diethylamine; isopropyl alcohol / Resolution of racemate

2: hydrogen / palladium 10% on activated carbon / methanol / 2 h / 20 °C

With hydrogen; palladium 10% on activated carbon; In methanol; hexane; diethylamine; isopropyl alcohol;