Bupivacaine

Base Information Edit

Chemical Name:Bupivacaine
CAS No.:2180-92-9
Molecular Formula:C₁₈H₂₈N₂O
Molecular Weight:288.433
Hs Code.:
Mol file:2180-92-9.mol

Synonyms:MARCAINE;BUPIVACAINE;BUPIVACAINE BASE;(.+/-.)-1-Butyl-2,6-pipecoloxylidide;1-Butyl-2-(2,6-xylycarbamoyl)piperidine;1-Butyl-2,6-pipecoloxylidide;1-butyl-2’,6’-pipecoloxylidide;1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamid

Suppliers and Price of Bupivacaine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemtos
Bupivacaine
10 mg
$ 1200.00

Biosynth Carbosynth
Bupivacaine
100 mg
$ 50.00

Total 134 raw suppliers

Chemical Property of Bupivacaine Edit

Chemical Property:

Melting Point:107.5-108°
Refractive Index:1.5700 (estimate)
Boiling Point:436oC at 760 mmHg
PKA:8.09; also reported as 8.17(at 25℃)
Flash Point:140.9oC
PSA：32.34000
Density:1.014g/cm3
LogP:3.90740
Water Solubility.:101.5mg/L(25 oC)

Purity/Quality:

99% ^*data from raw suppliers

Bupivacaine ^*data from reagent suppliers

Safty Information:

Pictogram(s): T+
Hazard Codes:T+
Statements: 26/27/28-38-41
Safety Statements: 22-26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Uses Anesthetic (local). Like lidocaine and mepivacaine, bupivacaine is used in infiltration, spinal, and epidural anesthesia in blocking nerve transmission. Its most distinctive property is its long-lasting action. It is used for surgical intervention in urology and in lower thoracic surgery from 3 to 5 h in length, and in abdominal surgery lasting from 45 to 60 min. It is used to block the trifacial nerve, the sacral and brachial plexuses, in resetting dislocations, in epidural anesthesia, and during Cesarian sections.
Therapeutic Function Local anesthetic

Technology Process of Bupivacaine

There total 10 articles about Bupivacaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%