(3R,4R)-1-(tert-butoxycarbonyl)-4-methylpyrrolidine-3-carboxylic acid

Base Information

• Chemical Name: (3R,4R)-1-(tert-butoxycarbonyl)-4-methylpyrrolidine-3-carboxylic acid
• CAS No.: 1119512-35-4
• Molecular Formula: C11H19NO4
• Molecular Weight: 229.27286
• Mol file: 1119512-35-4.mol

Synonyms:(3R,4R)-1-(tert-butoxycarbonyl)-4-methylpyrrolidine-3-carboxylic acid;(3R,4R)-1-[(tert-butoxy)carbonyl]-4-Methylpyrrolidine-3-carboxyl

Chemical Property of (3R,4R)-1-(tert-butoxycarbonyl)-4-methylpyrrolidine-3-carboxylic acid

Chemical Property:

• PSA: 66.84000
• LogP: 1.51190
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

(3R,4R)-1-(tert-Butoxycarbonyl)-4-methylpyrrolidine-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3R,4R)-1-(tert-butoxycarbonyl)-4-methylpyrrolidine-3-carboxylic acid

There total 9 articles about (3R,4R)-1-(tert-butoxycarbonyl)-4-methylpyrrolidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

racemic trans-4-methylpyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester → racemic trans-4-methylpyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester (1119512-35-4,1393524-21-4)

Guidance literature:

With water; sodium hydroxide; In methanol; at 20 ℃; for 2h;

Reference yield: 90.0%

1-tert-butyl 3-ethyl (±)-4-methylpyrrolidine-1,3-dicarboxylate (1434126-87-0,1434126-89-2) → racemic trans-4-methylpyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester (1119512-35-4,1393524-21-4)

Guidance literature:

With water; sodium hydroxide; In methanol; at 20 ℃; for 2h;

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + (3S,4S)-trans-1-benzyl-4-methyl-pyrrolidine-3-carboxylic acid ethyl ester (261896-27-9) → (S,S)-trans-4-methylpyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester (1119512-35-4,1393524-21-4)

Guidance literature:

di-tert-butyl dicarbonate; (3S,4S)-trans-1-benzyl-4-methyl-pyrrolidine-3-carboxylic acid ethyl ester; With 5%-palladium/activated carbon; hydrogen; In ethanol; at 45 - 50 ℃; for 48h; under 11251.1 - 15001.5 Torr; Autoclave; Inert atmosphere;

With water; sodium hydroxide; at 20 ℃; for 2h;

upstream raw materials:

1-tert-butyl 3-ethyl (±)-4-methylpyrrolidine-1,3-dicarboxylate

di-tert-butyl dicarbonate

(3S,4S)-trans-1-benzyl-4-methyl-pyrrolidine-3-carboxylic acid ethyl ester

racemic trans-1-benzyl-4-methyl-pyrrolidine-3-carboxylic acid ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1119512-35-4 (3R,4R)-1-(tert-butoxycarbonyl)-4-methylpyrrolidine-3-carboxylic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send