Chemical Property of Resminostat
Chemical Property:
- PKA:8.68±0.23(Predicted)
- PSA：103.51000
- Density:1.28±0.1 g/cm3 (20 oC 760 Torr), Calc.*
- LogP:3.22640
- Solubility.:Soluble in DMSO
- XLogP3:0.9
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:6
- Exact Mass:349.10962727
- Heavy Atom Count:24
- Complexity:548
- Purity/Quality:
-
99%, *data from raw suppliers
Resminostat *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CN(C)CC1=CC=C(C=C1)S(=O)(=O)N2C=CC(=C2)C=CC(=O)NO
- Isomeric SMILES:CN(C)CC1=CC=C(C=C1)S(=O)(=O)N2C=CC(=C2)/C=C/C(=O)NO
- Recent ClinicalTrials:Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS)
- Recent EU Clinical Trials:A multicentre, double blind, randomised, placebo controlled, Phase II trial to evaluate Resminostat for maintenance treatment of patients with advanced stage (Stage IIB-IVB) mycosis fungoides (MF) or Sézary Syndrome (SS) that have achieved disease control with systemic therapy – the RESMAIN Study
- Recent NIPH Clinical Trials:A Clinical trial for Resminostat to Investigate the Effect of Food
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Uses
Resminostat is an oral histone deacetylase (HDAC) inhibitor. It inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells.
