tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Base Information

Chemical Name:tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate
CAS No.:1073354-70-7
Molecular Formula:C16H29BN2O5
Molecular Weight:322.212
Hs Code.:2934999090
European Community (EC) Number:640-499-8
DSSTox Substance ID:DTXSID50584921
Wikidata:Q82476678
Mol file:1073354-70-7.mol

Synonyms:1073354-70-7;tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate;1-Boc-3,5-dimethylpyrazole-4-boronic acid pinacol ester;tert-butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylate;C16H27BN2O4;MFCD09027070;tert-butyl 3,5-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate;SCHEMBL111352;DTXSID50584921;GNLNGVZPEKSDAR-UHFFFAOYSA-N;BCP32759;AKOS015893169;FS-5816;SB12220;(1-(TERT-BUTOXYCARBONYL)-3,5-DIMETHYL-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER;SY247818;B6026;CS-0036251;O10003;EN300-7384095;J-001848;J-524513;1-Boc-3,5-diMethylpyrazol-4-boronic acid pinacol ester;1-Boc-3,5-dimethyl-1H-pyrazole-4-boronic Acid Pinacol Ester;1-Boc-3,5-dimethylpyrazole-4-boronic acid pinacol ester, 97%;1-tert-Butoxycarbonyl-3,5-dimethylpyrazole-4-boronic acid pinacol ester;3,5-dimethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazole-1-carboxylic acid tert-butyl ester;tert-Butyl3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Suppliers and Price of tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Boc-3,5-dimethylpyrazole-4-boronic acid pinacol ester
500mg
$ 160.00

TCI Chemical
1-(tert-Butoxycarbonyl)-3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
1G
$ 102.00

TCI Chemical
1-(tert-Butoxycarbonyl)-3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
200MG
$ 31.00

SynQuest Laboratories
3,5-Dimethyl-1H-pyrazole-4-boronic acid, pinacol ester, N1-Boc protected
1 g
$ 240.00

SynQuest Laboratories
3,5-Dimethyl-1H-pyrazole-4-boronic acid, pinacol ester, N1-Boc protected
250 mg
$ 108.00

Sigma-Aldrich
1-Boc-3,5-dimethylpyrazole-4-boronic acid pinacol ester 97%
250mg
$ 46.10

Sigma-Aldrich
1-Boc-3,5-dimethylpyrazole-4-boronic acid pinacol ester 97%
1g
$ 127.00

Matrix Scientific
tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate 95+%
1g
$ 189.00

Matrix Scientific
tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate 95+%
10g
$ 788.00

Matrix Scientific
tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate 95+%
5g
$ 504.00

Total 23 raw suppliers

Chemical Property of tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Chemical Property:

Melting Point:109-113 °C
Boiling Point:421.0±55.0 °C(Predicted)
PKA:0.03±0.12(Predicted)
PSA：62.58000
Density:1.07±0.1 g/cm3(Predicted)
LogP:2.58230
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:322.2063875
Heavy Atom Count:23
Complexity:459

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Boc-3,5-dimethylpyrazole-4-boronic acid pinacol ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=C(N(N=C2C)C(=O)OC(C)(C)C)C

Technology Process of tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

There total 1 articles about tert-Butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 857530-80-4
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

: 24424-99-5
di-tert-butyl dicarbonate

: 1073354-70-7
tert-butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Guidance literature:: With sodium carbonate; In 1,4-dioxane; at 20 ℃; for 48h;

Reference yield: 76.0%

: 1073354-70-7
tert-butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

: 103697-17-2
(4-iodophenyl)phosphonate de diethyle

: C₂₀H₂₉N₂O₅P

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In 1,4-dioxane; at 100 ℃; for 6h; Inert atmosphere;
DOI:10.1515/znb-2019-0170

Reference yield: 60.0%

: 1073354-70-7
tert-butyl 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

: 5-bromo-N-cyclopentyl-N-(2,4-dimethoxybenzyl)-2-methoxybenzenesulfonamide

: N-cyclopentyl-N-(2,4-dimethoxybenzyl)-5-(3,5-dimethyl-1H-pyrazol-4-yl)-2-methoxybenzenesulfonamide

Guidance literature:: With dichloro-[1,3-bis(2,6-diisopropylpenyl)-2-imidazolidinyliden]-(3-chloropyridyl)palladium(II); caesium carbonate; In 1,4-dioxane; water; N,N-dimethyl-formamide; at 90 ℃; for 12h; Inert atmosphere; Microwave irradiation;
DOI:10.1039/c4md00182f