Chemical Property of Demethylzeylasteral
Chemical Property:
- Boiling Point:663.6±55.0 °C(Predicted)
- PKA:4.78±0.70(Predicted)
- PSA：111.90000
- Density:1.31
- LogP:5.78820
- Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
- Solubility.:DMSO (Slightly), Methanol (Slightly)
- XLogP3:6.2
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:2
- Exact Mass:480.25118886
- Heavy Atom Count:35
- Complexity:1000
- Purity/Quality:
-
99%, *data from raw suppliers
Demethylzeylasteral *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC12CCC(CC1C3(CCC4(C5=CC(=C(C(=C5C(=O)C=C4C3(CC2)C)C=O)O)O)C)C)(C)C(=O)O
- Isomeric SMILES:C[C@]12CC[C@@](C[C@H]1[C@@]3(CC[C@]4(C5=CC(=C(C(=C5C(=O)C=C4[C@]3(CC2)C)C=O)O)O)C)C)(C)C(=O)O
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Uses
Demethylzeylasteral is a natural product as new inhibitor to block the Bcl-XL-Bid interaction. Also, it is an immunosuppressive monomer isolated from the root xylem of Tripterygium wilfordii. It exhibits inhibition towards the glucuronidation elimination reaction of SN-38.
