piperidin-2-ylmethyl trifluoromethanesulfonate

Base Information

• Chemical Name: piperidin-2-ylmethyl trifluoromethanesulfonate
• CAS No.: 127075-48-3
• Molecular Formula: C6H13NO3S
• Molecular Weight: 247
• Hs Code.: 2933399090
• Mol file: 127075-48-3.mol

Synonyms:piperidin-2-ylmethyl trifluoromethanesulfonate;2-Piperidinemethanesulfonic acid

Chemical Property of piperidin-2-ylmethyl trifluoromethanesulfonate

Chemical Property:

• PSA: 63.78000
• Density: 1.261
• LogP: 2.40430

Purity/Quality:

98% ^*data from raw suppliers

2-Piperidinemethanesulfonicacid 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of piperidin-2-ylmethyl trifluoromethanesulfonate

There total 4 articles about piperidin-2-ylmethyl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(RS)-1-Aza-8-thiabicyclo<4.2.0>octan-8,8-dioxid (87357-14-0) → (RS)-2-Piperidinmethansulfonsaeure (127075-48-3)

Guidance literature:

With hydrogenchloride; In water; for 0.0833333h;

DOI:10.1002/ardp.19903230208

Reference yield:

(R,S)-2-piperidylmethanethiol (85657-12-1) → (RS)-2-Piperidinmethansulfonsaeure (127075-48-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / HCl, Cl₂ / CCl₄; ethanol / T < 10 deg C

2: 81 percent / NH₃ / CHCl₃

3: 94 percent / verd. HCl / H₂O / 0.08 h

With hydrogenchloride; ammonia; chlorine; In tetrachloromethane; ethanol; chloroform; water;

DOI:10.1002/ardp.19903230208

Reference yield:

(R,S)-2-piperidylmethanesulfonyl chloride hydrochloride (85657-13-2) → (RS)-2-Piperidinmethansulfonsaeure (127075-48-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / NH₃ / CHCl₃

2: 94 percent / verd. HCl / H₂O / 0.08 h

With hydrogenchloride; ammonia; In chloroform; water;

DOI:10.1002/ardp.19903230208

upstream raw materials:

(RS)-1-Aza-8-thiabicyclo<4.2.0>octan-8,8-dioxid

(R,S)-2-piperidylmethanethiol

(R,S)-2-piperidylmethanesulfonyl chloride hydrochloride

(RS)-9-Imino-1-aza-8-thiabicyclo<4.3.0>nonan-hydrobromid-thioharnstoff

Refernces