4-Chloro-2-phenylthieno[2,3-d]pyrimidine

Base Information

• Chemical Name: 4-Chloro-2-phenylthieno[2,3-d]pyrimidine
• CAS No.: 56843-80-2
• Molecular Formula: C12H7ClN2S
• Molecular Weight: 246.71500
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID30406177
• Wikidata: Q72457622
• Mol file: 56843-80-2.mol

Synonyms:4-chloro-2-phenylthieno[2,3-d]pyrimidine;56843-80-2;DTXSID30406177;AKOS002665470;AM20040734;CS-0366683;FT-0752790;A15658

Chemical Property of 4-Chloro-2-phenylthieno[2,3-d]pyrimidine

Chemical Property:

• Vapor Pressure: 0.00217mmHg at 25°C
• Melting Point: 148℃
• Boiling Point: 299.1ºC at 760 mmHg
• Flash Point: 134.7ºC
• PSA: 54.02000
• Density: 1.396g/cm3
• LogP: 4.01170
• Storage Temp.: 2-8°C
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 246.0018471
• Heavy Atom Count: 16
• Complexity: 245

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-2-phenylthieno[2,3-d]pyrimidine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC3=C(C=CS3)C(=N2)Cl

Technology Process of 4-Chloro-2-phenylthieno[2,3-d]pyrimidine

There total 2 articles about 4-Chloro-2-phenylthieno[2,3-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-phenyl-3H-thieno[2,3-d]pyrimidin-4-one (56843-76-6) → 4-chloro-2-phenylthieno[2,3-d]pyrimidine (56843-80-2)

Guidance literature:

With trichlorophosphate; for 4h; Reflux;

DOI:10.1039/b915274a

Reference yield:

2-benzamidothiophene-3-carboxamide (55654-16-5) → 4-chloro-2-phenylthieno[2,3-d]pyrimidine (56843-80-2)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH / 65 - 95 °C

2: POCl₃, Py / Heating

With pyridine; sodium hydroxide; trichlorophosphate;

Reference yield: 97.0%

4-chloro-2-phenylthieno[2,3-d]pyrimidine (56843-80-2) → 4-chloro-6-iodo-2-phenylthieno[2,3-d]pyrimidine (1201805-74-4)

Guidance literature:

4-chloro-2-phenylthieno[2,3-d]pyrimidine; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; CdCl₂*TMEDA; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;

With iodine; In tetrahydrofuran; hexane; Inert atmosphere;

DOI:10.1039/b915274a

upstream raw materials:

2-phenyl-3H-thieno[2,3-d]pyrimidin-4-one

2-benzamidothiophene-3-carboxamide

Downstream raw materials:

4-(morpholin-4-yl)-2-phenylthieno[2,3-d]pyrimidine

4-hydrazino-2-phenyl-thieno[2,3-d]pyrimidine

2-phenyl-thieno[2,3-d]pyrimidine

5-phenyl-thieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 56843-80-2 4-chloro-2-phenylthieno[2,3-d]pyrimidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send