16alpha-Hydroxydehydroepiandrosterone

Base Information

Chemical Name:16alpha-Hydroxydehydroepiandrosterone
CAS No.:1232-73-1
Molecular Formula:C19H28 O3
Molecular Weight:304.43
Hs Code.:
UNII:WU2DU6GA72
DSSTox Substance ID:DTXSID90153892
Nikkaji Number:J14.213A
Wikipedia:16%CE%B1-Hydroxy-DHEA
Wikidata:Q4551082
Metabolomics Workbench ID:35345
ChEMBL ID:CHEMBL2057645
Mol file:1232-73-1.mol

Synonyms:16 alpha-hydroxydehydroisoandrosterone;16 beta-hydroxydehydroepiandrosterone;16-hydroxydehydroepiandrosterone;16-hydroxydehydroepiandrosterone, (16beta)-isomer;16-hydroxydehydroepiandrosterone, (3alpha,16alpha)-isomer;16alpha-hydroxy-dehydroepiandrosterone;3 beta,16 alpha-dihydroxyandrost-5-en-17-one;3 beta,16 beta-dihydroxyandrost-5-en-17-one;3,16-dihydroxyandrost-5-en-17-one;3beta,16alpha-dihydroxyandrost-5-en-17-one

Suppliers and Price of 16alpha-Hydroxydehydroepiandrosterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
16-ALPHA-HYDROXYDEHYDROEPIANDROSTERONE 95.00%
5MG
$ 451.20

Total 6 raw suppliers

Chemical Property of 16alpha-Hydroxydehydroepiandrosterone

Chemical Property:

Vapor Pressure:8.56E-11mmHg at 25°C
Boiling Point:469.6°Cat760mmHg
Flash Point:251.9°C
PSA：57.53000
Density:1.19g/cm³
LogP:2.85000
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:304.20384475
Heavy Atom Count:22
Complexity:539

Purity/Quality:

99% ^*data from raw suppliers

16-ALPHA-HYDROXYDEHYDROEPIANDROSTERONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC(CC1=CCC3C2CCC4(C3CC(C4=O)O)C)O
Isomeric SMILES:C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3C[C@H](C4=O)O)C)O
General Description (3b,16a)-3,16-Dihydroxy-Androst-5-en-17-one, also known as 16α-hydroxydehydroepiandrosterone (16α-OH-DHEA), is a steroid derivative of DHEA with a hydroxyl group at the 16α-position. It serves as a precursor for synthesizing further modified steroids, such as 7-oxo or 7-hydroxy derivatives, as demonstrated in studies involving oxidation and reduction reactions. The 16α-hydroxylation of steroids is catalyzed by enzymes like CYP154C5, which exhibits high regioselectivity for this position, though modifications in enzyme structure or substrate can alter product formation. Additionally, its metabolism may involve cytochrome P450 enzymes like CYP3A7, which show interindividual variability in activity, potentially influencing endogenous steroid processing.

Technology Process of 16alpha-Hydroxydehydroepiandrosterone

There total 21 articles about 16alpha-Hydroxydehydroepiandrosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%