2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine

Base Information

Chemical Name:2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine
CAS No.:878733-59-6
Molecular Formula:C12H18N2O
Molecular Weight:206.28
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30424634
Wikidata:Q82237289
Mol file:878733-59-6.mol

Synonyms:2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine;878733-59-6;2-[2-(pyrrolidin-1-yl)ethoxy]aniline;2-(2-pyrrolidin-1-ylethoxy)aniline;SCHEMBL1031593;DTXSID30424634;AKOS B033181;JTDDQVZMAYCEPA-UHFFFAOYSA-N;BBL036333;STK346737;AKOS000113492;2-(2-pyrrolidin-1-yl-ethoxy)phenylamine;VS-13425;BB 0258194

Suppliers and Price of 2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine
1g
$ 485.00

American Custom Chemicals Corporation
2-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE 95.00%
500MG
$ 796.95

AK Scientific
2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine
1g
$ 704.00

Total 5 raw suppliers

Chemical Property of 2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine

Chemical Property:

PSA：38.49000
LogP:2.26250
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:206.141913202
Heavy Atom Count:15
Complexity:181

Purity/Quality:

97% ^*data from raw suppliers

2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CCOC2=CC=CC=C2N

Technology Process of 2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine

There total 3 articles about 2-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1379464-89-7
tert-butyl (2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)carbamate

: 878733-59-6
2-(2-pyrrolidin-1-yl-ethoxy)phenylamine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 21h;
DOI:10.1021/ml300037k

Reference yield:

: 5050-41-9
N-(2-chloroethyl)-pyrrolidine

: 878733-59-6
2-(2-pyrrolidin-1-yl-ethoxy)phenylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 8 h / Reflux

2: trifluoroacetic acid / dichloromethane / 21 h / 0 - 20 °C

With potassium carbonate; trifluoroacetic acid; In dichloromethane; acetonitrile;
DOI:10.1021/ml300037k

Reference yield:

: 186663-74-1
tert-butyl (2-hydroxyphenyl)carbamate

: 878733-59-6
2-(2-pyrrolidin-1-yl-ethoxy)phenylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 8 h / Reflux

2: trifluoroacetic acid / dichloromethane / 21 h / 0 - 20 °C

With potassium carbonate; trifluoroacetic acid; In dichloromethane; acetonitrile;
DOI:10.1021/ml300037k