5-Chloro-4-(trifluoromethyl)pyridin-2-amine

Base Information

Chemical Name:5-Chloro-4-(trifluoromethyl)pyridin-2-amine
CAS No.:1095823-39-4
Molecular Formula:C6H4ClF3N2
Molecular Weight:196.559
Hs Code.:2933399990
DSSTox Substance ID:DTXSID30697604
Nikkaji Number:J3.204.421B
Wikidata:Q82627543
Mol file:1095823-39-4.mol

Synonyms:5-chloro-4-(trifluoromethyl)pyridin-2-amine;1095823-39-4;2-AMINO-5-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE;MFCD18255015;SCHEMBL600673;DTXSID30697604;RVHOCQUEFYITIV-UHFFFAOYSA-N;CS-M1607;AKOS015999824;AB74629;DS-15760;SY029148;AM20050664;FT-0714833;5-Chloro-4-(trifluoromethyl)pyridine-2-amine;2-PyridinaMine,5-chloro-4-(trifluoroMethyl)-;5-chloro-4-(trifluoromethyl)-2-pyridinylamine;EN300-316678;AS-813/43416515;2-PYRIDINAMINE, 5-CHLORO-4-(TRIFLUOROMETHYL)-

Suppliers and Price of 5-Chloro-4-(trifluoromethyl)pyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Chloro-4-(trifluoromethyl)pyridin-2-amine
500mg
$ 310.00

SynQuest Laboratories
2-Amino-5-chloro-4-(trifluoromethyl)pyridine
250 mg
$ 42.00

SynQuest Laboratories
2-Amino-5-chloro-4-(trifluoromethyl)pyridine
1 g
$ 128.00

Matrix Scientific
5-Chloro-4-(trifluoromethyl)pyridin-2-amine 95+%
5g
$ 1195.00

Matrix Scientific
5-Chloro-4-(trifluoromethyl)pyridin-2-amine 95+%
1g
$ 345.00

Crysdot
5-Chloro-4-(trifluoromethyl)pyridin-2-amine 97%
5g
$ 681.00

Chemenu
2-Amino-5-chloro-4-(trifluoromethyl)pyridine 97%
5g
$ 800.00

Chemenu
2-Amino-5-chloro-4-(trifluoromethyl)pyridine 97%
1g
$ 248.00

Chemcia Scientific
5-Chloro-4-trifluoromethyl-pyridin-2-ylamine ＞97%
0.5 G
$ 140.00

Apolloscientific
2-Amino-5-chloro-4-(trifluoromethyl)pyridine
250mg
$ 26.00

Total 40 raw suppliers

Chemical Property of 5-Chloro-4-(trifluoromethyl)pyridin-2-amine

Chemical Property:

PSA：39.64000
LogP:2.26610
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:196.0015103
Heavy Atom Count:12
Complexity:161

Purity/Quality:

99%, ^*data from raw suppliers

5-Chloro-4-(trifluoromethyl)pyridin-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CN=C1N)Cl)C(F)(F)F

Technology Process of 5-Chloro-4-(trifluoromethyl)pyridin-2-amine

There total 2 articles about 5-Chloro-4-(trifluoromethyl)pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 106447-97-6
2-amino-4-(trifluoromethyl)pyridine

: 1095823-39-4
5-chloro-4-(trifluoromethyl)pyridin-2-amine

Guidance literature:: With Selectfluor; lithium chloride; In N,N-dimethyl-formamide; at 15 ℃; for 12h; regioselective reaction; Inert atmosphere; Schlenk technique; Sealed tube;
DOI:10.1039/c9ob00972h

Reference yield:

: 118-52-5
1,3-dichloro-5,5-dimethylhydantoin

: 106447-97-6
2-amino-4-(trifluoromethyl)pyridine

: 1095823-39-4
5-chloro-4-(trifluoromethyl)pyridin-2-amine

Guidance literature:: In N,N-dimethyl-formamide;

Reference yield: 49.0%

: 1095823-39-4
5-chloro-4-(trifluoromethyl)pyridin-2-amine

: 1095823-37-2
C₁₃H₁₂N₂O₄S

: 1095823-41-8
C₁₉H₁₄ClF₃N₄O₃S

Guidance literature:: C₁₃H₁₂N₂O₄S; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 0.25h;

5-chloro-4-(trifluoromethyl)pyridin-2-amine; With pyridine; In acetonitrile; at 20 ℃;