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Nemonoxacin

Base Information
  • Chemical Name:Nemonoxacin
  • CAS No.:378746-64-6
  • Molecular Formula:C20H25N3O4
  • Molecular Weight:371.436
  • Hs Code.:
  • UNII:P94L0PVO94
  • ChEMBL ID:CHEMBL1213456
  • DSSTox Substance ID:DTXSID10958907
  • Metabolomics Workbench ID:149852
  • NCI Thesaurus Code:C174838
  • Nikkaji Number:J3.442.639B
  • Wikidata:Q15425793
  • Wikipedia:Nemonoxacin
  • Mol file:378746-64-6.mol
Nemonoxacin

Synonyms:nemonoxacin;TG 873870;TG-873870;TG873870

Suppliers and Price of Nemonoxacin
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • American Custom Chemicals Corporation
  • NEMONOXACIN 95.00%
  • 5MG
  • $ 498.75
Total 37 raw suppliers
Chemical Property of Nemonoxacin
Chemical Property:
  • Boiling Point:606.4±55.0 °C(Predicted) 
  • PKA:6.52±0.50(Predicted) 
  • PSA:97.79000 
  • Density:1.335±0.06 g/cm3(Predicted) 
  • LogP:2.98200 
  • XLogP3:0.4
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:7
  • Rotatable Bond Count:4
  • Exact Mass:371.18450629
  • Heavy Atom Count:27
  • Complexity:647
Purity/Quality:

98% ,99% , *data from raw suppliers

NEMONOXACIN 95.00% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1CC(CN(C1)C2=C(C3=C(C=C2)C(=O)C(=CN3C4CC4)C(=O)O)OC)N
  • Isomeric SMILES:C[C@H]1C[C@@H](CN(C1)C2=C(C3=C(C=C2)C(=O)C(=CN3C4CC4)C(=O)O)OC)N
  • Recent ClinicalTrials:Efficacy and Safety of Nemonoxacin vs Levofloxacin in Adult Patients With Community-Acquired Pneumonia
  • Description Nemonoxacin is a novel nonfluorinated quinolone and broad-spectrum antibiotic for the treatment of drug-resistant bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA) and quinolone- resistant MRSA as well as quinolone-resistant Streptococcus pneumonia. The drug was originally discovered by Procter & Gamble Pharmaceuticals (P&GP). It was codeveloped by TaiGen Biotechnology for development in Asia and by Warner Chilcott for development in the United States and Europe and was first approved by the China Food and Drug Administration (CFDA).
Technology Process of Nemonoxacin

There total 2 articles about Nemonoxacin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

Guidance literature:
C25H33N3O6; With hydrogenchloride; water; In dichloromethane; at 35 - 40 ℃; for 12h;
With sodium hydroxide; water; at 50 - 65 ℃; pH=7 - 8.1;

Reference yield:

Guidance literature:
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