Berubicin

Base Information

Chemical Name:Berubicin
CAS No.:677017-23-1
Molecular Formula:C34H35NO11
Molecular Weight:633.64
Hs Code.:
UNII:6QPN83HK2M
DSSTox Substance ID:DTXSID70217986
NCI Thesaurus Code:C83552
ChEMBL ID:CHEMBL2110580
Mol file:677017-23-1.mol

Synonyms:Berubicin;677017-23-1;WP 769;Berubicin [INN];UNII-6QPN83HK2M;6QPN83HK2M;WP-769;(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-6-methyl-5-phenylmethoxyoxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;WP769;Berubicin (oral, cancer);D03AZR;BERUBICIN [WHO-DD];CHEMBL2110580;DTXSID70217986;RTA-769;BB178714;Berubicin (intravenous), Reata Pharmaceuticals;Berubicin (oral, cancer), Reata Pharmaceuticals;Q27265347;Anthracycline derivative topoisomerase II inhibitor (cancer), Reata;Anthracycline derivative topoisomerase II inhibitor (cancer), MD Anderson;Anthracycline topoisomerase II inhibitor (oral, cancer), MD Anderson Cancer Center;Anthracycline topoisomerase II inhibitor (oral, cancer), Reata Pharmaceuticals;(8S,10S)-10-((3-AMINO-4-O-BENZYL-2,3,6-TRIDEOXY-A-L-LYXO-HEXOPYRANOSYL)OXY)-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-7,8,9,10-TETRAHYDROTETRACENE-5,12-DIONE;5,12-NAPHTHACENEDIONE, 10-((3-AMINO-2,3,6-TRIDEOXY-4-O-(PHENYLMETHYL)-.ALPHA.-L-LYXO-HEXOPYRANOSYL)OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-, (8S,10S)-

Suppliers and Price of Berubicin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BERUBICIN 95.00%
5MG
$ 498.71

Total 19 raw suppliers

Chemical Property of Berubicin

Chemical Property:

Boiling Point:835.4±65.0 °C(Predicted)
PKA:7.35±0.60(Predicted)
PSA：195.07000
Density:1.51±0.1 g/cm3(Predicted)
LogP:2.92610
XLogP3:3.3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:8
Exact Mass:633.22101093
Heavy Atom Count:46
Complexity:1130

Purity/Quality:

99%, ^*data from raw suppliers

BERUBICIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)OCC6=CC=CC=C6
Isomeric SMILES:C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)OCC6=CC=CC=C6
Recent ClinicalTrials:A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme
Recent EU Clinical Trials:Evaluation of the safety and efficacy of Berubicin in the treatment of central nervous system lymphomas- BERUBICIN
Use Description I couldn't find specific information about a chemical compound or substance referred to as "WP 769" in my knowledge base, which is current up to September 2021. It's possible that "WP 769" could refer to a proprietary product, research compound, or a term specific to a certain industry or field that emerged after my last update. To provide you with accurate information on its uses and roles in different fields, I would need more context or updated information. I recommend consulting relevant scientific literature, databases, or industry sources for the most recent and detailed information regarding "WP 769" and its applications.

Technology Process of Berubicin

There total 1 articles about Berubicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: