Chemical Property of ipilimumab
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Chemical Property:
- Purity/Quality:
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95%min SEC-HPLC *data from raw suppliers
Ipilimumab *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
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Description
Ipilimumab is a CTLA-4 blocking antibody that was approved by the
U.S. FDA in March 2011 for the treatment of unresectable or metastatic
melanoma. Therefore, ipilimumab has an indirect effect on tumors that is
mediated through blockade of CTLA-4 negative signaling and
augmentation of T-cell activity. It is one of a handful of
immunostimulatory drugs (e.g., aldesleukin and interferon alfa-2b) now approved for cancer therapy.
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Uses
Treatment of
oncology disease and HIV infection.
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Clinical Use
Antineoplastic agent:
Treatment of advanced (unresectable or metastatic)
melanoma in adults who have received prior therapy
