2-Pyrazinecarboxamide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris-

Base Information

Chemical Name:2-Pyrazinecarboxamide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris-
CAS No.:390800-88-1
Molecular Formula:C57H69B3N12O9
Molecular Weight:1098.68
Hs Code.:
Mol file:390800-88-1.mol

Synonyms:Pyrazinecarboxamide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris- (9CI);

Suppliers and Price of 2-Pyrazinecarboxamide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
BortezomibTrimer
5mg
$ 155.00

Chemenu
N,N'',N''''-((1S,1''S,1''''S)-(((1R,1''R,1''''R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(2-oxo-1-phenylethane-2,1-diyl))tris(pyrazine-2-carboxamide) 95%+
1g
$ 1235.00

Cayman Chemical
Bortezomib-d15
1mg
$ 278.00

Cayman Chemical
Bortezomib-d15
500μg
$ 147.00

Total 16 raw suppliers

Chemical Property of 2-Pyrazinecarboxamide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris-

Chemical Property:

Boiling Point:1277.7±65.0 °C(Predicted)
PKA:11.46±0.46(Predicted)
PSA：279.63000
Density:1.26±0.1 g/cm3(Predicted)
LogP:7.82370
Storage Temp.:-20°C Freezer

Purity/Quality:

98%,99%, ^*data from raw suppliers

BortezomibTrimer ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.

Technology Process of 2-Pyrazinecarboxamide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris-

There total 4 articles about 2-Pyrazinecarboxamide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-methylbutylidene]imino[(1S)-2-oxo-1-(phenylmethyl)-2,1-ethanediyl]]]tris- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 205393-22-2
N-[(1S)-1[[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]carbonyl]-2-benzyl]2-pyrazine carboxamide

: (1S,2S,3R,5S)-pinanediol N-(2-pyrazinecarbonyl)-L-phenylalanine-L-leucine boronate

: 390800-88-1
bortezomib

: N-(2-pyrazinecarbonyl)-L-phenylalanine-L-leucine boronic anhydride

Guidance literature:: With Dihydroxy-isobutyl-boran; In methanol; n-heptane; water; at 21.6 - 28.6 ℃; for 16.38h; Product distribution / selectivity; Industry scale;