Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)-

Base Information

• Chemical Name: Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)-
• CAS No.: 220099-91-2
• Deprecated CAS: 909910-24-3
• Molecular Formula: C13H16N2O
• Molecular Weight: 216.28
• Hs Code.: 2934999090
• UNII: 2B218X5QIY
• DSSTox Substance ID: DTXSID40944616
• Nikkaji Number: J3.283.371C
• Wikipedia: AZD0328
• Wikidata: Q17014648
• Pharos Ligand ID: MNDRX5NJBDYP
• Metabolomics Workbench ID: 153188
• ChEMBL ID: CHEMBL2151437
• Mol file: 220099-91-2.mol

Synonyms:AZD 0328;AZD-0328;AZD0328;spiro(1-azabicyclo(2.2.2)octane-3,2'(3H)-furo(2,3-b)pyridine)

Chemical Property of Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)-

Chemical Property:

• Boiling Point: 361.1±42.0 °C(Predicted)
• PKA: 9.59±0.20(Predicted)
• PSA: 25.36000
• Density: 1.26±0.1 g/cm3(Predicted)
• LogP: 1.41880
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 216.126263138
• Heavy Atom Count: 16
• Complexity: 288

Purity/Quality:

>98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CN2CCC1C3(C2)CC4=C(O3)N=CC=C4
• Isomeric SMILES: C1CN2CCC1[C@@]3(C2)CC4=C(O3)N=CC=C4
• Recent ClinicalTrials: Parkinson's Disease With Mild Cognitive Impairment Treated With Nicotinic Agonist Drug

Technology Process of Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)-

There total 1 articles about Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine] (220099-89-8,220099-91-2)

Guidance literature:

Reference yield:

spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine] (220099-89-8,220099-91-2) → 5'-bromospiro[1-azabicyclo[2.2.2]octane-3,2'-(3'H)-furo[2,3-b]pyridine] (220099-92-3)

Guidance literature:

With bromine; sodium acetate; In acetic acid;

Downstream raw materials:

5'-bromospiro[1-azabicyclo[2.2.2]octane-3,2'-(3'H)-furo[2,3-b]pyridine]