6-Bromo-3-hydroxypyrazine-2-carboxamide

Base Information

Chemical Name:6-Bromo-3-hydroxypyrazine-2-carboxamide
CAS No.:259793-88-9
Molecular Formula:C₅H₄BrN₃O₂
Molecular Weight:218.01
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30430790
Nikkaji Number:J2.689.142F
Wikidata:Q82244500
ChEMBL ID:CHEMBL4164322
Mol file:259793-88-9.mol

Synonyms:6-Bromo-3-hydroxypyrazine-2-carboxamide;259793-88-9;5-bromo-2-oxo-1H-pyrazine-3-carboxamide;2-Pyrazinecarboxamide, 6-bromo-3,4-dihydro-3-oxo-;MFCD20528005;SCHEMBL1337909;CHEMBL4164322;DTXSID30430790;6-Bromo-3-hydroxy-2-carboxamide;KZBREXQQUFIWKD-UHFFFAOYSA-N;AMY25052;BCP32172;CS-M1515;AKOS016004601;3-hydroxy-6-bromopyrazine-2-carboxamide;6-bromo-3-hydroxy-2-pyrazinecarboxamide;DS-16928;SY102916;EN300-4314047;6-Bromo-3-hydroxypyrazine-2-carboxylic acid amide;A854201;6-Bromo-3-hydroxypyrazine-2-carboxamide(KSM precursor)

Suppliers and Price of 6-Bromo-3-hydroxypyrazine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
6-Bromo-3-hydroxypyrazine-2-carboxamide 97%
5g
$ 2916.00

Matrix Scientific
6-Bromo-3-hydroxypyrazine-2-carboxamide 97%
1g
$ 1062.00

CSNpharm
6-Bromo-3-hydroxypyrazine-2-carboxamide
100mg
$ 45.00

ChemScene
2-Pyrazinecarboxamide,6-bromo-3,4-dihydro-3-oxo- 95.42%
5g
$ 501.00

ChemScene
2-Pyrazinecarboxamide,6-bromo-3,4-dihydro-3-oxo- 95.42%
250mg
$ 55.00

ChemScene
2-Pyrazinecarboxamide,6-bromo-3,4-dihydro-3-oxo- 95.42%
1g
$ 134.00

Chemenu
6-bromo-3-hydroxypyrazine-2-carboxamide 95%+
1g
$ 218.00

Chemenu
6-bromo-3-hydroxypyrazine-2-carboxamide 95%+
250mg
$ 71.00

Chemenu
6-bromo-3-hydroxypyrazine-2-carboxamide 95%+
5g
$ 580.00

Chemcia Scientific
6-Bromo-3-oxo-3,4-dihydro-pyrazine-2-carboxylicacidamide 95%
5 G
$ 625.00

Total 80 raw suppliers

Chemical Property of 6-Bromo-3-hydroxypyrazine-2-carboxamide

Chemical Property:

PKA:9.02±0.60(Predicted)
PSA：89.10000
Density:2.23±0.1 g/cm3(Predicted)
LogP:0.74390
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:216.94869
Heavy Atom Count:11
Complexity:282

Purity/Quality:

99%min, ^*data from raw suppliers

6-Bromo-3-hydroxypyrazine-2-carboxamide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(N=C(C(=O)N1)C(=O)N)Br
Uses 6-Bromo-3-hydroxypyrazine-2-carboxamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.

Technology Process of 6-Bromo-3-hydroxypyrazine-2-carboxamide

There total 3 articles about 6-Bromo-3-hydroxypyrazine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.1%