Cyclobutanecarboxylic acid, 1-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-1-piperidinyl]methyl]-

Base Information

• Chemical Name: Cyclobutanecarboxylic acid, 1-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-1-piperidinyl]methyl]-
• CAS No.: 871022-19-4
• Molecular Formula: C₁₇H₃₀N₂O₄
• Molecular Weight: 326.436
• Mol file: 871022-19-4.mol

Synonyms:1-[[4-[[(tert-Butoxycarbonyl)amino]methyl]piperidin-1-yl]methyl]cyclobutanecarboxylic acid;

Chemical Property of Cyclobutanecarboxylic acid, 1-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-1-piperidinyl]methyl]-

Chemical Property:

• PSA: 78.87000
• LogP: 2.80680

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclobutanecarboxylic acid, 1-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-1-piperidinyl]methyl]-

There total 1 articles about Cyclobutanecarboxylic acid, 1-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-1-piperidinyl]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Ethyl 1-[(4-{[(tert-butoxycarbonyl)amino]methyl}piperidin-1-yl)-methyl]cyclobutanecarboxylate → 1-[(4-{[(tert-butoxycarbonyl)amino]methyl}piperidin-1-yl)methyl]cyclobutane carboxylic acid (871022-19-4)

Guidance literature:

Ethyl 1-[(4-{[(tert-butoxycarbonyl)amino]methyl}piperidin-1-yl)-methyl]cyclobutanecarboxylate; With sodium hydroxide; In ethanol; water; at 50 ℃; for 4h;

With hydrogenchloride; In ethanol; water; at 0 ℃; pH=5 - 6;

Refernces

• 1、 -. "Benzimidazolone carboxylic acid derivatives". Page/Page column 32. . Retrieved 2008/06/13.