5-amino-1-methyl-3-(trifluoromethyl)-1H-Pyrazole-4-carboxylic acid

Base Information

Chemical Name:5-amino-1-methyl-3-(trifluoromethyl)-1H-Pyrazole-4-carboxylic acid
CAS No.:317806-51-2
Molecular Formula:C6H6F3N3O2
Molecular Weight:209.126
Hs Code.:2933199090
DSSTox Substance ID:DTXSID60436008
Wikidata:Q82251178
Mol file:317806-51-2.mol

Synonyms:317806-51-2;5-amino-1-methyl-3-(trifluoromethyl)-1H-Pyrazole-4-carboxylic acid;5-amino-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxylic Acid;5-Amino-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid;1H-Pyrazole-4-carboxylicacid,5-amino-1-methyl-3-(trifluoromethyl)-(9CI);SCHEMBL4625019;DTXSID60436008;AMY12073;MFCD12827717;AKOS015850908;AT21773;AC-27611;BS-25252;A820986;J-504726;5-amino-1-methyl-3-trifluoromethylpyrazole-4-carboxylic acid;1H-Pyrazole-4-carboxylicacid,5-aMino-1-Methyl-3-(trifluoroMethyl);5-amino-1-methyl-3-(trifluoromethyl)-1H-Pyrazole-4-carboxylicacid

Suppliers and Price of 5-amino-1-methyl-3-(trifluoromethyl)-1H-Pyrazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Amino-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicAcid
500mg
$ 155.00

Matrix Scientific
5-Amino-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylicacid 95%+
5g
$ 1260.00

Matrix Scientific
5-Amino-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylicacid 95%+
1g
$ 306.00

Crysdot
5-Amino-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid 95+%
5g
$ 392.00

Chemenu
5-Amino-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylicacid 95%
5g
$ 370.00

American Custom Chemicals Corporation
5-AMINO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 95.00%
5G
$ 2656.50

Alichem
5-Amino-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
5g
$ 316.80

Advanced Chemicals Intermediatesced Chemicals Intermediates
5-Amino-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylicacid 95%+
5g
$ 507.50

Acints
5-Amino-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylicacid 95%+
5g
$ 507.50

Acints
5-Amino-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylicacid 95%+
1g
$ 123.25

Total 19 raw suppliers

Chemical Property of 5-amino-1-methyl-3-(trifluoromethyl)-1H-Pyrazole-4-carboxylic acid

Chemical Property:

Boiling Point:340.6±42.0 °C(Predicted)
PKA:3.67±0.36(Predicted)
PSA：81.14000
Density:1.73±0.1 g/cm3(Predicted)
LogP:1.30050
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:209.04121093
Heavy Atom Count:14
Complexity:245

Purity/Quality:

97% ^*data from raw suppliers

5-Amino-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=C(C(=N1)C(F)(F)F)C(=O)O)N

Technology Process of 5-amino-1-methyl-3-(trifluoromethyl)-1H-Pyrazole-4-carboxylic acid

There total 2 articles about 5-amino-1-methyl-3-(trifluoromethyl)-1H-Pyrazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 317806-48-7
ethyl 5-amino-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate

: 317806-51-2
5-amino-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: With hydrogenchloride; sodium hydroxide; In water;

Reference yield:

: sodium 3-cyano-4-ethoxy-1,1,1-trifluoro-4-oxobut-2-en-2-olate

: 317806-51-2
5-amino-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: carbonic acid dimethyl ester; trifluoroacetic acid / acetone / Molecular sieve; Reflux

2: water; potassium hydroxide / ethanol / Reflux

With water; carbonic acid dimethyl ester; trifluoroacetic acid; potassium hydroxide; In ethanol; acetone;