5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine

Base Information

Chemical Name:5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine
CAS No.:1215074-30-8
Molecular Formula:C12H7BrF3N
Molecular Weight:302.093
Hs Code.:
Mol file:1215074-30-8.mol

Synonyms:Lafutidine Pibutidine intermediate

Suppliers and Price of 5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Bromo-2-(4-(trifluoromethyl)phenyl)pyridine 95+%
1g
$ 629.00

Chemenu
5-Bromo-2-(4-(trifluoromethyl)phenyl)pyridine 95%
1g
$ 594.00

AOBChem
3-Bromo-6-(4-trifluoromethylphenyl)pyridine 97%
1g
$ 467.00

American Custom Chemicals Corporation
5-BROMO-2-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE 95.00%
5MG
$ 497.24

Alichem
5-Bromo-2-(4-(trifluoromethyl)phenyl)pyridine
1g
$ 506.88

Total 13 raw suppliers

Chemical Property of 5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine

Chemical Property:

Appearance/Colour:Light yellow liquid
Melting Point:106-108 °C(Solv: hexane (110-54-3))
Boiling Point:304.2±37.0 °C(Predicted)
PKA:1.48±0.25(Predicted)
PSA：12.89000
Density:1.528±0.06 g/cm3(Predicted)
LogP:4.52990
Storage Temp.:2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

5-Bromo-2-(4-(trifluoromethyl)phenyl)pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine

There total 4 articles about 5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 624-28-2
2,5-dibromopyridine

: 718628-25-2
(4-(trifluoromethyl)phenyl)zinc(II) iodide

: 1215074-30-8
5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 20 ℃; for 0.5h; regioselective reaction; Inert atmosphere;
DOI:10.5012/bkcs.2014.35.1.280

Reference yield: 63.0%

: 455-13-0
4-Iodobenzotrifluoride

: 5-bromo-2-(triethylgermyl)pyridine

: 1215074-30-8
5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; silver tetrafluoroborate; In N,N-dimethyl-formamide; at 80 ℃; for 72h; chemoselective reaction;
DOI:10.1002/anie.201910060

Reference yield: 50.0%

: 624-28-2
2,5-dibromopyridine

: 128796-39-4
4-trifluoromethylphenylboronic acid

: 1215074-30-8
5-bromo-2-(4-(trifluoromethyl)phenyl)pyridine

Guidance literature:: With palladium diacetate; potassium carbonate; triphenylphosphine; In methanol; acetonitrile; at 50 ℃; for 24h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2013.10.065