Ethyl 3-methylthieno[2,3-c]isothiazole-5-carboxylate

Base Information

Chemical Name:Ethyl 3-methylthieno[2,3-c]isothiazole-5-carboxylate
CAS No.:82000-57-5
Molecular Formula:C₉H₉NO₂S₂
Molecular Weight:227.308
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00513862
Wikidata:Q82373870
Mol file:82000-57-5.mol

Synonyms:Ethyl 3-methylthieno[2,3-c]isothiazole-5-carboxylate;82000-57-5;ETHYL 3-METHYLTHIENO[2,3-C][1,2]THIAZOLE-5-CARBOXYLATE;Ethyl3-methylthieno[2,3-c]isothiazole-5-carboxylate;DTXSID00513862;AMY36663;FT-0732963

Suppliers and Price of Ethyl 3-methylthieno[2,3-c]isothiazole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl3-methylthieno[2,3-c]isothiazole-5-carboxylate 95+%
1g
$ 564.00

American Custom Chemicals Corporation
ETHYL-3-METHYLTHIENO[2,3-C]ISOTHIAZOLE-5-CARBOXYLATE 95.00%
5MG
$ 500.05

Alichem
Ethyl3-methylthieno[2,3-c]isothiazole-5-carboxylate
1g
$ 487.60

Total 6 raw suppliers

Chemical Property of Ethyl 3-methylthieno[2,3-c]isothiazole-5-carboxylate

Chemical Property:

PSA：95.67000
LogP:2.84290
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:227.00747088
Heavy Atom Count:14
Complexity:237

Purity/Quality:

98% ^*data from raw suppliers

Ethyl3-methylthieno[2,3-c]isothiazole-5-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(SN=C2S1)C

Technology Process of Ethyl 3-methylthieno[2,3-c]isothiazole-5-carboxylate

There total 2 articles about Ethyl 3-methylthieno[2,3-c]isothiazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 82000-48-4
ethyl-2-(4-cyano-5-methylisothiazol-3-ylthio)acetate

: 82000-57-5
ethyl 3-methylthieno<2,3-c>isothiazole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / EtONa / dimethylformamide / 1 h / 20 °C

2: 1). sodium nitrite, H₂SO₄, 2.) hypophosphorous acid, CuO / 1.) 0 deg C, 2h, 2). 0 deg C, 3h,

With sulfuric acid; sodium ethanolate; hypophosphorous acid; copper(II) oxide; sodium nitrite; In N,N-dimethyl-formamide;

Reference yield:

: 82000-54-2
ethyl 4-amino-3-methylthieno-<2,3-c>isothiazole-5-carboxylate

: 82000-57-5
ethyl 3-methylthieno<2,3-c>isothiazole-5-carboxylate

Guidance literature:: With sulfuric acid; hypophosphorous acid; copper(II) oxide; sodium nitrite; Yield given. Multistep reaction; 1.) 0 deg C, 2h, 2). 0 deg C, 3h,;