4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, a-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)-

Base Information

Chemical Name:4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, a-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)-
CAS No.:192049-49-3
Molecular Formula:C23H21N3O5S
Molecular Weight:451.49
Hs Code.:
Mol file:192049-49-3.mol

4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, a-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)-

Synonyms:IKUFRGFORUKHMI-DENIHFKCSA-N;4-Nitrobenzyl 2-((1R,5R)-3-benzyl-7-oxo-4-thia-2,6-diazabicyclo-[3.2.0]hept-2-en-6-yl)-3-methylbu;5-Methyl-2-nitrophenyl 2-{3-benzyl-7-oxo-4-thia-2,6-diazabicyclo[3.2.0]hept-2-en-1-yl}-3-Methylbut-2-enoate;72. 4-nitrobenzyl 2-((1R,5R)-3-benzyl-7-oxo-4-thia-2,6-diaza bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl -but-2-enoate;4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, α-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)-;4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, a-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)-

Suppliers and Price of 4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, a-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
4-Nitrobenzyl2-((1r,5r)-3-benzyl-7-oxo-4-thia-2,6-diazabicyclo[3.2.0]hept-2-en-6-yl)-3-methylbut-2-enoate
1g
$ 1164.00

Alichem
4-Nitrobenzyl2-((1r,5r)-3-benzyl-7-oxo-4-thia-2,6-diazabicyclo[3.2.0]hept-2-en-6-yl)-3-methylbut-2-enoate
250mg
$ 499.20

Total 7 raw suppliers

Chemical Property of 4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, a-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)-

Chemical Property:

PSA：130.09000
LogP:3.75350

Purity/Quality:

97% ^*data from raw suppliers

4-Nitrobenzyl2-((1r,5r)-3-benzyl-7-oxo-4-thia-2,6-diazabicyclo[3.2.0]hept-2-en-6-yl)-3-methylbut-2-enoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, a-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)-

There total 6 articles about 4-Thia-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid, a-(1-methylethylidene)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (1R,5R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.8%

: C₂₃H₂₁N₃O₅S

: 192049-49-3
2-((1R)-3-benzyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-2-enoic acid 4-nitro-benzyl ester

Guidance literature:: With hydrogenchloride; N,N,N',N'-tetramethylguanidine; In water; at 30 ℃; for 0.0833333h; Reagent/catalyst; Inert atmosphere; Darkness; Large scale;

Reference yield:

: 3-benzyl-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-7-one

: 81779-73-9
chloroxoacetic acid (4-nitrophenyl)methyl ester

: 192049-49-3
(3-Benzyl₇-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-2-enoic Acid 4-Nitro-benzyl Ester

Guidance literature:: With triethylamine; In dichloromethane;

Reference yield:

: 27487-21-4
p-nitrobenzyl benzylpenicillinate

: 192049-49-3
2-((1R)-3-benzyl-7-oxo-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-2-enoic acid 4-nitro-benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium sulfite / water / Large scale

1.2: 0.5 h / Large scale

2.1: toluene; cyclohexane / 90 - 100 °C / Inert atmosphere; Large scale

3.1: N,N,N',N'-tetramethylguanidine / 30 °C / Inert atmosphere; Large scale

With sodium sulfite; N,N,N',N'-tetramethylguanidine; In cyclohexane; water; toluene;