N5,N5-dimethyl-1H-pyrazole-3,5-diamine

Base Information

• Chemical Name: N5,N5-dimethyl-1H-pyrazole-3,5-diamine
• CAS No.: 935667-36-0
• Molecular Formula: C₅H₁₀N₄
• Molecular Weight: 126.161
• Mol file: 935667-36-0.mol

Synonyms:N5,N5-dimethyl-1H-pyrazole-3,5-diamine;1H-Pyrazole-3,5-diamine, N5,N5-dimethyl-

Chemical Property of N5,N5-dimethyl-1H-pyrazole-3,5-diamine

Chemical Property:

• Boiling Point: 336.9±22.0 °C(Predicted)
• PKA: 16.48±0.10(Predicted)
• PSA: 57.94000
• Density: 1.246±0.06 g/cm3(Predicted)
• LogP: 0.63910
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

N5,N5-dimethyl-1H-pyrazole-3,5-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N5,N5-dimethyl-1H-pyrazole-3,5-diamine

There total 3 articles about N5,N5-dimethyl-1H-pyrazole-3,5-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(2Z)-3-(dimethylamino)-3-(methylthio)acrylonitrile (178483-39-1) → N5,N5-dimethyl-1H-pyrazole-3,5-diamine (935667-36-0,732981-76-9)

Guidance literature:

With hydrazine; In ethanol; Heating / reflux;

Reference yield: 69.0%

3-(dimethylamino)-3-(methylthio)acrylonitrile (935667-35-9) → N5,N5-dimethyl-1H-pyrazole-3,5-diamine (935667-36-0,732981-76-9)

Guidance literature:

With hydrazine; In ethanol; at 85 ℃;

Reference yield:

C5H8N2S → N5,N5-dimethyl-1H-pyrazole-3,5-diamine (935667-36-0,732981-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran; hexane / 0 - 25 °C

2: hydrazine hydrate / ethanol / 85 °C

With hydrazine hydrate; In tetrahydrofuran; ethanol; hexane;

DOI:10.1021/jm1011319

upstream raw materials:

(2Z)-3-(dimethylamino)-3-(methylthio)acrylonitrile

3-(dimethylamino)-3-(methylthio)acrylonitrile