N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine

Base Information

Chemical Name:N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine
CAS No.:169205-87-2
Molecular Formula:C14H12BrN5
Molecular Weight:330.187
Hs Code.:
UNII:72M7S95J3U
DSSTox Substance ID:DTXSID101257447
Nikkaji Number:J693.958I
Pharos Ligand ID:B3U6DLL5HMS6
ChEMBL ID:CHEMBL328216
Mol file:169205-87-2.mol

Synonyms:bpdq;169205-87-2;N4-(3-bromophenyl)quinazoline-4,6,7-triamine;N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine;4-N-(3-bromophenyl)quinazoline-4,6,7-triamine;72M7S95J3U;N-(3-Bromophenyl)quinazoline-4,6,7-triamine;UNII-72M7S95J3U;CHEMBL328216;4,6,7-Quinazolinetriamine, N4-(3-bromophenyl)-;4-[(3-Bromophenyl)amino]-6,7-diaminoquinazoline;D0B4PH;K00041;BDBM3303;SCHEMBL7221302;4-Anilinoquinazoline deriv. 54;DTXSID101257447;HSCI1_000040;AKOS025149794;4-(3-bromoanilino)-6,7-diaminoquinazoline;4[ (3-Bromophenyl)aminol-6,7-diaminoquinazoline;J-010514;N*4*-(3-Bromo-phenyl)-quinazoline-4,6,7-triamine;BRD-K65185756-001-01-0

Suppliers and Price of N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-[(3-BROMOPHENYL)AMINO]-6,7-DIAMINOQUINAZOLINE 95.00%
5MG
$ 498.37

Total 1 raw suppliers

Chemical Property of N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine

Chemical Property:

PSA：89.85000
LogP:4.53570
XLogP3:2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:329.02761
Heavy Atom Count:20
Complexity:329

Purity/Quality:: 4-[(3-BROMOPHENYL)AMINO]-6,7-DIAMINOQUINAZOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Br)NC2=NC=NC3=CC(=C(C=C32)N)N

Technology Process of N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine

There total 5 articles about N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 169205-92-9
7-amino-4-<(3-bromophenyl)amino>-6-nitroquinazoline

: 169205-87-2
4-[(3-bromophenyl)amino]-6,7-diaminoquinazoline

Guidance literature:: With hydrogenchloride; iron; In ethanol; water;
DOI:10.1021/jm00018a008

Reference yield:

: 169205-91-8
7-acetamido-4-<(3-bromophenyl)amino>-6-nitroquinazoline

: 169205-87-2
4-[(3-bromophenyl)amino]-6,7-diaminoquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / KOH / methanol; H₂O / 0.5 h / Heating

2: 65 percent / Fe, aq. HCl / ethanol; H₂O

With hydrogenchloride; potassium hydroxide; iron; In methanol; ethanol; water;
DOI:10.1021/jm00018a008

Reference yield:

: 169205-90-7
7-acetamido-6-nitroquinazolin-4(3H)-one

: 169205-87-2
4-[(3-bromophenyl)amino]-6,7-diaminoquinazoline

Guidance literature:: Multi-step reaction with 4 steps

1: POCl₃ / 2 h / Heating

2: propan-2-ol

3: 87 percent / KOH / methanol; H₂O / 0.5 h / Heating

4: 65 percent / Fe, aq. HCl / ethanol; H₂O

With hydrogenchloride; potassium hydroxide; iron; trichlorophosphate; In methanol; ethanol; water; isopropyl alcohol;
DOI:10.1021/jm00018a008