7-Benzothiazolecarboxylicacid,Methylester

Base Information

• Chemical Name: 7-Benzothiazolecarboxylicacid,Methylester
• CAS No.: 1038509-28-2
• Molecular Formula: C9H7NO2S
• Molecular Weight: 193.22238
• Hs Code.: 2934200090
• Mol file: 1038509-28-2.mol

Synonyms:7-Benzothiazolecarboxylicacid,Methylester;Benzothiazole-7-carboxylic acid Methyl ester;Methyl 1,3-benzothiazole-7-carboxylate

Chemical Property of 7-Benzothiazolecarboxylicacid,Methylester

Chemical Property:

• Boiling Point: 309.9±15.0 °C(Predicted)
• PKA: -0.83±0.30(Predicted)
• PSA: 67.43000
• Density: 1.340±0.06 g/cm3(Predicted)
• LogP: 2.08290
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Methylbenzo[d]thiazole-7-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Benzothiazolecarboxylicacid,Methylester

There total 3 articles about 7-Benzothiazolecarboxylicacid,Methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2-aminobenzo[d]thiazole-7-carboxylate (209459-11-0) → methyl benzo[d]thiazole-7-carboxylate (1038509-28-2)

Guidance literature:

With isopentyl nitrite; In tetrahydrofuran; for 4h; Heating / reflux;

Reference yield:

Methyl 3-aminobenzoate (4518-10-9) → methyl benzo[d]thiazole-7-carboxylate (1038509-28-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sulfuric acid / chlorobenzene / -10 °C

1.2: -10 - 100 °C

2.1: bromine; acetic acid / 0 - 70 °C

3.1: isopentyl nitrite / tetrahydrofuran / 4 h / Reflux

With sulfuric acid; bromine; acetic acid; isopentyl nitrite; In tetrahydrofuran; chlorobenzene;

Reference yield:

methyl 3-thioureidobenzoate (192948-00-8) → methyl benzo[d]thiazole-7-carboxylate (1038509-28-2)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine; acetic acid / 0 - 70 °C

2: isopentyl nitrite / tetrahydrofuran / 4 h / Reflux

With bromine; acetic acid; isopentyl nitrite; In tetrahydrofuran;

upstream raw materials:

methyl 2-aminobenzo[d]thiazole-7-carboxylate

Methyl 3-aminobenzoate

methyl 3-thioureidobenzoate

Downstream raw materials:

benzo[d]thiazole-7-carboxylic acid

methyl 2-aminobenzo[d]thiazole-7-carboxylate