3-Amino-5,6-dichloropyrazine-2-carbonitrile

Base Information

Chemical Name:3-Amino-5,6-dichloropyrazine-2-carbonitrile
CAS No.:14340-28-4
Molecular Formula:C5H2Cl2N4
Molecular Weight:189.004
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20526176
Wikidata:Q82394392
Mol file:14340-28-4.mol

Synonyms:3-Amino-5,6-dichloropyrazine-2-carbonitrile;14340-28-4;SCHEMBL10087543;DTXSID20526176;YSJNSSANBISNQN-UHFFFAOYSA-N;MFCD19443188;AKOS016002790;2-amino-3-cyano-5,6-dichloropyrazine;AC-27252;BS-42364;O10937;A884974

Suppliers and Price of 3-Amino-5,6-dichloropyrazine-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Amino-5,6-dichloropyrazine-2-carbonitrile 95+%
10g
$ 1255.00

Crysdot
3-Amino-5,6-dichloropyrazine-2-carbonitrile 95+%
25g
$ 2095.00

Crysdot
3-Amino-5,6-dichloropyrazine-2-carbonitrile 95+%
5g
$ 940.00

Crysdot
3-Amino-5,6-dichloropyrazine-2-carbonitrile 95+%
1g
$ 416.00

Chemenu
3-Amino-5,6-dichloropyrazine-2-carbonitrile 95%
1g
$ 389.00

Chemenu
3-Amino-5,6-dichloropyrazine-2-carbonitrile 95%
5g
$ 879.00

Chemenu
3-Amino-5,6-dichloropyrazine-2-carbonitrile 95%
25g
$ 1959.00

Chemenu
3-Amino-5,6-dichloropyrazine-2-carbonitrile 95%
10g
$ 1174.00

American Custom Chemicals Corporation
3-AMINO-5,6-DICHLOROPYRAZINE-2-CARBONITRILE 95.00%
5MG
$ 500.42

Alichem
3-Amino-5,6-dichloropyrazine-2-carbonitrile
10g
$ 1608.00

Total 20 raw suppliers

Chemical Property of 3-Amino-5,6-dichloropyrazine-2-carbonitrile

Chemical Property:

PSA：76.32000
LogP:1.16738
Storage Temp.:2-8°C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:187.9656515
Heavy Atom Count:11
Complexity:188

Purity/Quality:

97% ^*data from raw suppliers

3-Amino-5,6-dichloropyrazine-2-carbonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(#N)C1=C(N=C(C(=N1)Cl)Cl)N

Technology Process of 3-Amino-5,6-dichloropyrazine-2-carbonitrile

There total 3 articles about 3-Amino-5,6-dichloropyrazine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 14229-27-7
3-amino-5,6-dichloro-2-pyrazinecarboxamide

: 14340-28-4
3-amino-5,6-dichloropyrazine-2-carbonitrile

Guidance literature:: With trichlorophosphate; In toluene; at 80 ℃; for 5h; Inert atmosphere;
DOI:10.1016/j.bmcl.2011.12.123

Reference yield:

: 1458-18-0
methyl 6-amino-2,3-dichloropyrazine-5-carboxylate

: 14340-28-4
3-amino-5,6-dichloropyrazine-2-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia / 11.5 h / -80 °C / Inert atmosphere; Reflux

2: trichlorophosphate / toluene / 5 h / 80 °C / Inert atmosphere

With ammonia; trichlorophosphate; In toluene;
DOI:10.1016/j.bmcl.2011.12.123