2-Chloro-5-nitroisonicotinic acid

Base Information

Chemical Name:2-Chloro-5-nitroisonicotinic acid
CAS No.:907545-47-5
Molecular Formula:C6H3ClN2O4
Molecular Weight:202.554
Hs Code.:2933399090
European Community (EC) Number:692-777-3
DSSTox Substance ID:DTXSID30593793
Wikidata:Q82488353
Mol file:907545-47-5.mol

Synonyms:2-chloro-5-nitroisonicotinic acid;907545-47-5;2-chloro-5-nitropyridine-4-carboxylic acid;2-Chloro-5-nitro-isonicotinic acid;2-Chloro-5-nitro isonicotinic acid;2-chloro-5-nitro-4-Pyridinecarboxylic acid;MFCD14584664;TPC-PY016;SCHEMBL801584;DTXSID30593793;YIKBSICAFIIUER-UHFFFAOYSA-N;AMY10228;AKOS015991288;AKOS015993881;BG-0014;SB39789;AC-27080;SY110462;DB-078791;2-Chloro-5-nitro-pyridine-4-carboxylic acid;CS-0022412;EN300-99079;A850840;J-508872;Z1269108738

Suppliers and Price of 2-Chloro-5-nitroisonicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-chloro-5-nitroisonicotinicAcid
250mg
$ 200.00

SynQuest Laboratories
2-Chloro-5-nitroisonicotinic acid
250 mg
$ 61.00

SynQuest Laboratories
2-Chloro-5-nitroisonicotinic acid
1 g
$ 168.00

SynQuest Laboratories
2-Chloro-5-nitroisonicotinic acid
5 g
$ 488.00

Matrix Scientific
2-Chloro-5-nitropyridine-4-carboxylicacid >97%
1g
$ 357.00

Matrix Scientific
2-Chloro-5-nitropyridine-4-carboxylicacid >97%
500mg
$ 265.00

Crysdot
2-Chloro-5-nitroisonicotinicacid 98%
25g
$ 223.00

Crysdot
2-Chloro-5-nitroisonicotinicacid 98%
100g
$ 886.00

Chemenu
2-Chloro-5-nitropyridine-4-carboxylicacid 98%
5g
$ 491.00

Chemenu
2-Chloro-5-nitropyridine-4-carboxylicacid 98%
1g
$ 179.00

Total 48 raw suppliers

Chemical Property of 2-Chloro-5-nitroisonicotinic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:480.153°C at 760 mmHg
PKA:1.08±0.25(Predicted)
Flash Point:244.188°C
PSA：96.01000
Density:1.702g/cm³
LogP:1.86460
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:201.9781343
Heavy Atom Count:13
Complexity:229

Purity/Quality:

99%, ^*data from raw suppliers

2-chloro-5-nitroisonicotinicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CN=C1Cl)[N+](=O)[O-])C(=O)O

Technology Process of 2-Chloro-5-nitroisonicotinic acid

There total 1 articles about 2-Chloro-5-nitroisonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 23056-33-9
2-chloro-4-methyl-5-nitro-pyridine

: 907545-47-5
2-chloro-5-nitro-pyridine-4-carboxylic acid

Guidance literature:: With chromium(VI) oxide; sulfuric acid; at 0 - 20 ℃;

Reference yield: 51.6%

: 907545-47-5
2-chloro-5-nitro-pyridine-4-carboxylic acid

: 122-51-0
orthoformic acid triethyl ester

: 907545-64-6
ethyl 2-chloro-5-nitroisonicotinate

Guidance literature:: at 20 ℃; for 3h;

Reference yield:

: 907545-47-5
2-chloro-5-nitro-pyridine-4-carboxylic acid

: 1445877-06-4
2-methyl-3-(2-methyl-3-(trifluoromethyl)benzyl)-5-morpholino-3H-imidazo[4,5-b]pyridine-7-carboxylic acid

Guidance literature:: Multi-step reaction with 7 steps

1.1: potassium carbonate / 4 h / 100 °C

2.1: copper diacetate; potassium tert-butylate; methylamine hydrochloride / N,N-dimethyl-formamide / 16 h / 60 °C

3.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; triethylamine / tetrahydrofuran / 16 h / 20 °C

4.1: acetic acid; hydrogen; palladium 10% on activated carbon / methanol / 16 h / 20 °C

5.1: 16 h / Reflux

6.1: sodium carbonate / N,N-dimethyl-formamide / 3 h / 80 °C

7.1: lithium hydroxide / tetrahydrofuran / 8 h / 50 °C

7.2: pH 1

With palladium 10% on activated carbon; potassium tert-butylate; hydrogen; methylamine hydrochloride; copper diacetate; sodium carbonate; potassium carbonate; acetic acid; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; lithium hydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;