(4-CHLORO-6-METHYL-PYRIDIN-2-YL)-METHANOL

Base Information

• Chemical Name: (4-CHLORO-6-METHYL-PYRIDIN-2-YL)-METHANOL
• CAS No.: 98280-32-1
• Molecular Formula: C₇H₈ClNO
• Molecular Weight: 157.6
• Hs Code.: 2933399090
• Mol file: 98280-32-1.mol

Synonyms:(4-CHLORO-6-METHYL-PYRIDIN-2-YL)-METHANOL;(4-Chloro-6-methyl-2-pyridinyl)methanol

Chemical Property of (4-CHLORO-6-METHYL-PYRIDIN-2-YL)-METHANOL

Chemical Property:

• Melting Point: 85-86℃
• Boiling Point: 245.8℃
• Flash Point: 102.4℃
• PSA: 33.12000
• Density: 1.263
• LogP: 1.53570
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(4-Chloro-6-methylpyridin-2-yl)methanol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-CHLORO-6-METHYL-PYRIDIN-2-YL)-METHANOL

There total 4 articles about (4-CHLORO-6-METHYL-PYRIDIN-2-YL)-METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic 4-chloro-6-methyl-2-pyridinylmethyl ester (339585-99-8) → 4-Chloro-2-hydroxymethyl-6-methylpyridine (98280-32-1)

Guidance literature:

With potassium hydroxide; In methanol; water;

Reference yield:

ethyl 4-chloro-6-methylpyridine-2-carboxylate (315494-03-2) → 4-Chloro-2-hydroxymethyl-6-methylpyridine (98280-32-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 2h; Heating / reflux;

Reference yield:

2,6-dimethyl-4-chloropyridine N-oxide (697-92-7) → 4-Chloro-2-hydroxymethyl-6-methylpyridine (98280-32-1)

Guidance literature:

With acetic anhydride; folgenden Erwaermen des Reaktionsgemisches mit wss.Salzsaeure;

upstream raw materials:

2,6-dimethyl-4-chloropyridine N-oxide

acetic 4-chloro-6-methyl-2-pyridinylmethyl ester

ethyl 4-chloro-6-methylpyridine-2-carboxylate

Downstream raw materials:

4-chloro-6-methylpicolinaldehyde