(2S)-2-Amino-3-hydroxypentanoic acid

Base Information

Chemical Name:(2S)-2-Amino-3-hydroxypentanoic acid
CAS No.:2280-42-4
Molecular Formula:C5H11 N O3
Molecular Weight:133.147
Hs Code.:2922509090
European Community (EC) Number:622-551-1
ChEMBL ID:CHEMBL11723
Nikkaji Number:J447.797I
Mol file:2280-42-4.mol

Synonyms:(2S)-2-Amino-3-hydroxypentanoic acid;DL-3-Hydroxynorvaline;CHEMBL11723;SCHEMBL498261;AKOS016010496;HY-W142133;AS-62988;DB-228654;CS-0201916;A822052;9EAE8E8F-DF4D-4535-857D-E44A51476697;50730-79-5

Suppliers and Price of (2S)-2-Amino-3-hydroxypentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
DL-3-Hydroxynorvaline ≥98% (TLC)
250mg
$ 226.00

Sigma-Aldrich
DL-3-Hydroxynorvaline ≥98% (TLC)
1g
$ 675.00

Crysdot
(2S)-2-Amino-3-hydroxypentanoicacid 95+%
1g
$ 574.00

Chemenu
(2S)-2-Amino-3-hydroxypentanoicacid 95%
1g
$ 542.00

American Custom Chemicals Corporation
3-HYDROXY NORVALINE 95.00%
5G
$ 2983.37

Total 8 raw suppliers

Chemical Property of (2S)-2-Amino-3-hydroxypentanoic acid

Chemical Property:

Melting Point:231.2℃
Boiling Point:328.4°Cat760mmHg
PKA:2.39±0.24(Predicted)
Flash Point:152.4°C
PSA：83.55000
Density:1.237g/cm³
LogP:-0.13050
Storage Temp.:−20°C
XLogP3:-2.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:133.07389321
Heavy Atom Count:9
Complexity:104

Purity/Quality:

98%,99%, ^*data from raw suppliers

DL-3-Hydroxynorvaline ≥98% (TLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCC(C(C(=O)O)N)O
Isomeric SMILES:CCC([C@@H](C(=O)O)N)O

Technology Process of (2S)-2-Amino-3-hydroxypentanoic acid

There total 15 articles about (2S)-2-Amino-3-hydroxypentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 2280-42-4
2-amino-3-hydroxy-valeric acid

: 2076-43-9,2076-54-2,2280-42-4,10148-66-0,10148-67-1,34042-00-7,50730-79-5,87585-07-7,104531-21-7,127984-23-0
(+/-)-erythro-β-hydroxynorvaline

: 2076-43-9,2076-54-2,2280-42-4,10148-66-0,10148-67-1,34042-00-7,50730-79-5,87585-07-7,104531-21-7,127984-23-0
(+/-)-threo-β-hydroxynorvaline

Guidance literature:: DOI:10.1246/bcsj.58.2889

Reference yield: 36.0%

: 2280-42-4
2-amino-3-hydroxy-valeric acid

: 2076-43-9,2076-54-2,2280-42-4,10148-66-0,10148-67-1,34042-00-7,50730-79-5,87585-07-7,104531-21-7,127984-23-0
(+/-)-erythro-β-hydroxynorvaline

: 2076-43-9,2076-54-2,2280-42-4,10148-66-0,10148-67-1,34042-00-7,50730-79-5,87585-07-7,104531-21-7,127984-23-0
(+/-)-threo-β-hydroxynorvaline

Guidance literature:: DOI:10.1246/bcsj.58.2889

Reference yield:

: 1439368-22-5
ethyl 2-(tert-butoxycarbonylamino)-3-oxo-pentanoate

: 34042-00-7
(2SR,3RS)-2-amino-3-hydroxypentanoic acid

: 2076-43-9,2076-54-2,2280-42-4,10148-66-0,10148-67-1,34042-00-7,50730-79-5,87585-07-7,104531-21-7,127984-23-0
(2SR,3SR)-2-amino-3-hydroxypentanoic acid

Guidance literature:: ethyl 2-(tert-butoxycarbonylamino)-3-oxo-pentanoate; With sodium tetrahydroborate; In tetrahydrofuran; ethanol; at 0 - 20 ℃; for 1h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; ethanol; water; at 130 ℃; for 0.5h; Inert atmosphere;