Pyridine-3,5-diyldimethanol

Base Information

Chemical Name:Pyridine-3,5-diyldimethanol
CAS No.:21636-51-1
Molecular Formula:C7H9NO2
Molecular Weight:139.154
Hs Code.:
DSSTox Substance ID:DTXSID20603274
Nikkaji Number:J2.201.431E
Wikidata:Q82500615
Mol file:21636-51-1.mol

Synonyms:Pyridine-3,5-diyldimethanol;21636-51-1;3,5-Dihydroxymethylpyridine;3,5-pyridinedimethanol;[5-(hydroxymethyl)pyridin-3-yl]methanol;(Pyridine-3,5-diyl)dimethanol;SCHEMBL2728918;DTXSID20603274;HYUQKAGYJAFMBA-UHFFFAOYSA-N;WAA63651;MFCD11617170;AKOS006315535;SB53127;(5-Hydroxymethyl-pyridin-3-yl)-methanol;DB-335459;CS-0378980;EN300-142348;Z1198341608

Suppliers and Price of Pyridine-3,5-diyldimethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3,5-PYRIDINEDIMETHANOL 95
1g
$ 417.00

Crysdot
Pyridine-3,5-diyldimethanol 97%
1g
$ 248.00

Crysdot
Pyridine-3,5-diyldimethanol 97%
5g
$ 772.00

Chemenu
pyridine-3,5-diyldimethanol 97%
5g
$ 729.00

Chemenu
pyridine-3,5-diyldimethanol 97%
1g
$ 234.00

American Custom Chemicals Corporation
3,5-DIHYDROXYMETHYLPYRIDINE 95.00%
1G
$ 1052.67

AccelPharmtech
3,5-Pyridinedimethanol 97.00%
25G
$ 4010.00

AccelPharmtech
3,5-Pyridinedimethanol 97.00%
5G
$ 2180.00

AccelPharmtech
3,5-Pyridinedimethanol 97.00%
1G
$ 1940.00

Total 18 raw suppliers

Chemical Property of Pyridine-3,5-diyldimethanol

Chemical Property:

Boiling Point:350.6±32.0 °C(Predicted)
PKA:13.40±0.10(Predicted)
PSA：53.35000
Density:1.261±0.06 g/cm3(Predicted)
LogP:0.06620
Storage Temp.:2-8°C
XLogP3:-0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:139.063328530
Heavy Atom Count:10
Complexity:87.6

Purity/Quality:

99% Min ^*data from raw suppliers

3,5-PYRIDINEDIMETHANOL 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC=C1CO)CO
Uses Pyridine-3,5-diyldimethanol is an intermediate for the synthesis of 5’-[(Desloratadine)methyl] Rupatadine (D290270), which is an impurity of the antihistaminic drug Rupatadine (R701650).

Technology Process of Pyridine-3,5-diyldimethanol

There total 6 articles about Pyridine-3,5-diyldimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 4591-55-3
dimethyl pyridine-3,5-dicarboxylate

: 21636-51-1
3,5-bis(hydroxymethyl)pyridine

Guidance literature:: lithium aluminium reduction;

Reference yield: 59.0%

: 21636-51-1
3,5-bis(hydroxymethyl)pyridine

Guidance literature:

Reference yield: 49.0%

: 15074-61-0
pyridine-3,5-dicarbonyl dichloride

: 21636-51-1
3,5-bis(hydroxymethyl)pyridine

Guidance literature:: With sodium tetrahydroborate; In water; at 0 - 20 ℃; for 1h; Schlenk technique; Inert atmosphere;
DOI:10.1055/s-0033-1338614