5-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Base Information

Chemical Name:5-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS No.:147677-00-7
Molecular Formula:C17H21N5O2
Molecular Weight:327.386
Hs Code.:

Synonyms:7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-(5-amino-2-ethoxyphenyl)-1,6-dihydro-1-methyl-3-propyl-;

Suppliers and Price of 5-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

There total 14 articles about 5-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 5-(2-Ethoxy-5-nitrophenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one

: 147677-00-7
5-(5-amino-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one

Guidance literature:: palladium on charcoal catalyst; In ethanol;

Reference yield:

: 139756-21-1
5-(2-ethoxy)-phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-one

: 147677-00-7
5-(5-amino-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium nitrate; sulfuric acid / 0.33 h / 0 °C

2: palladium on activated charcoal; hydrogen / methanol / 20 °C

With sulfuric acid; palladium on activated charcoal; hydrogen; potassium nitrate; In methanol;

Reference yield:

: 36983-31-0
ethyl 3-butyrylpyruvate

: 147677-00-7
5-(5-amino-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one

Guidance literature:: Multi-step reaction with 11 steps

1: hydrazine hydrate / acetic acid; 2-methoxy-ethanol / 100 °C

2: caesium carbonate / N,N-dimethyl-formamide / 20 °C

3: hydrogenchloride / water / 100 °C

4: nitric acid; sulfuric acid / 50 °C

5: thionyl chloride / Reflux

6: ammonium hydroxide / tetrahydrofuran / 2 h / Cooling with ice

7: palladium on activated charcoal; hydrogen / methanol / 30 °C / 2585.81 Torr

8: triethylamine / dichloromethane / 20 °C

9: sodium hydroxide; dihydrogen peroxide / ethanol; water / 100 °C

10: potassium nitrate; sulfuric acid / 0.33 h / 0 °C

11: palladium on activated charcoal; hydrogen / methanol / 20 °C

With hydrogenchloride; ammonium hydroxide; thionyl chloride; sulfuric acid; palladium on activated charcoal; hydrogen; dihydrogen peroxide; nitric acid; caesium carbonate; hydrazine hydrate; potassium nitrate; triethylamine; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; 2-methoxy-ethanol; water; acetic acid; N,N-dimethyl-formamide;