(1S,5R)-2-[(S)-alpha-Methylbenzyl]-6-oxa-2-azabicyclo[3.2.1]octan-7-one

Base Information

Chemical Name:(1S,5R)-2-[(S)-alpha-Methylbenzyl]-6-oxa-2-azabicyclo[3.2.1]octan-7-one
CAS No.:175476-91-2
Molecular Formula:C₁₄H₁₇NO₂
Molecular Weight:231.294
Hs Code.:
DSSTox Substance ID:DTXSID00445417
Nikkaji Number:J723.199G
Wikidata:Q82263803

Synonyms:PHE060;SCHEMBL7721947;DTXSID00445417;WJAONTKZWYIENP-UHTWSYAYSA-N;175476-91-2;(1s,5r)-2-((s)-1-phenylethyl)-6-oxa-2-azabicyclo[3.2.1]octan-7-one;(1S,5R)-2-[(S)-alpha-Methylbenzyl]-6-oxa-2-azabicyclo[3.2.1]octan-7-one

Suppliers and Price of (1S,5R)-2-[(S)-alpha-Methylbenzyl]-6-oxa-2-azabicyclo[3.2.1]octan-7-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (1S,5R)-2-[(S)-alpha-Methylbenzyl]-6-oxa-2-azabicyclo[3.2.1]octan-7-one

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:231.125928785
Heavy Atom Count:17
Complexity:299

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)N2CCC3CC2C(=O)O3
Isomeric SMILES:C[C@@H](C1=CC=CC=C1)N2CC[C@@H]3C[C@H]2C(=O)O3

Technology Process of (1S,5R)-2-[(S)-alpha-Methylbenzyl]-6-oxa-2-azabicyclo[3.2.1]octan-7-one

There total 3 articles about (1S,5R)-2-[(S)-alpha-Methylbenzyl]-6-oxa-2-azabicyclo[3.2.1]octan-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ((1R,3S,4S,7R)-3-Bromo-1,7-dimethyl-2-oxo-bicyclo[2.2.1]hept-7-yl)-methanesulfonic acid; compound with (1R,5S)-2-((S)-1-phenyl-ethyl)-6-oxa-2-aza-bicyclo[3.2.1]octan-7-one

: 175671-41-7
(1R,5S)-2-((S)-2-phenylethyl)-6-oxa-2-azabicyclo[3.2.1]octan-7-one

: 175476-91-2
(1S,5R)-2-((S)-2-phenylethyl)-6-oxa-2-azabicyclo[3.2.1]octan-7-one

Guidance literature:: With ammonium hydroxide; tert-butyl methyl ether; In water; for 0.0833333h; Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/jo9519874

Reference yield:

: ((1R,2R,4S,7R)-2-Bromo-1,7-dimethyl-3-oxo-bicyclo[2.2.1]hept-7-yl)-methanesulfonic acid; compound with (1S,5R)-2-((S)-1-phenyl-ethyl)-6-oxa-2-aza-bicyclo[3.2.1]octan-7-one

: 175671-41-7
(1R,5S)-2-((S)-2-phenylethyl)-6-oxa-2-azabicyclo[3.2.1]octan-7-one

: 175476-91-2
(1S,5R)-2-((S)-2-phenylethyl)-6-oxa-2-azabicyclo[3.2.1]octan-7-one

Guidance literature:: With ammonium hydroxide; tert-butyl methyl ether; In water; for 0.0833333h; Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/jo9519874