2-(3,4-Dimethoxybenzyl)-5-methyl-7-(2-oxo-6-phenyl-3-hexanyl)imidazo[5,1-f][1,2,4]triazin-4(1H)-one

Base Information

• Chemical Name: 2-(3,4-Dimethoxybenzyl)-5-methyl-7-(2-oxo-6-phenyl-3-hexanyl)imidazo[5,1-f][1,2,4]triazin-4(1H)-one
• CAS No.: 439083-78-0
• Molecular Formula: C27H30N4O4
• Molecular Weight: 474.56

Synonyms:Imidazo[5,1-f][1,2,4]triazin-4(1H)-one, 7-(1-acetyl-4-phenylbutyl)-2-[(3,4-dimethoxyphenyl)methyl]-5-methyl-;

Chemical Property of 2-(3,4-Dimethoxybenzyl)-5-methyl-7-(2-oxo-6-phenyl-3-hexanyl)imidazo[5,1-f][1,2,4]triazin-4(1H)-one

Chemical Property:

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SDS file from LookChem

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Technology Process of 2-(3,4-Dimethoxybenzyl)-5-methyl-7-(2-oxo-6-phenyl-3-hexanyl)imidazo[5,1-f][1,2,4]triazin-4(1H)-one

There total 1 articles about 2-(3,4-Dimethoxybenzyl)-5-methyl-7-(2-oxo-6-phenyl-3-hexanyl)imidazo[5,1-f][1,2,4]triazin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Acetyl-N-{1-[3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]-ethyl}-5-phenylpentanamide (439084-31-8) → 7-(1-acetyl-4-phenylbutyl)-2-(3,4-dimethoxybenzyl)-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (439083-78-0)

Guidance literature:

With trichlorophosphate;

Reference yield:

acetonitrile-water + 7-(1-acetyl-4-phenylbutyl)-2-(3,4-dimethoxybenzyl)-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (439083-78-0) → 2-(3,4-dimethoxybenzyl)-7-{(1S)-1-[(1R)-1-hydroxyethyl]-4-phenylbutyl}-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (439083-92-8)

Guidance literature:

With hydrogenchloride; sodium borohydrid; Zinc chloride; In methanol; dichloromethane;

Reference yield:

7-(1-acetyl-4-phenylbutyl)-2-(3,4-dimethoxybenzyl)-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one (439083-78-0) → 2-(3,4-dimethoxybenzyl)-7-[1-(1-hydroxyethyl)-4-phenylbutyl]-5-methylimidazo-[5,1-f][1,2,4]triazin-4(3H)-one

Guidance literature:

With sodium borohydrid;

upstream raw materials:

2-Acetyl-N-{1-[3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]-ethyl}-5-phenylpentanamide

Downstream raw materials:

2-(3,4-dimethoxybenzyl)-7-{(1S)-1-[(1R)-1-hydroxyethyl]-4-phenylbutyl}-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

2-(3,4-dimethoxybenzyl)-7-{(1S)-1-[(1S)-1-hydroxyethyl]-4-phenylbutyl}-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

2-(3,4-dimethoxybenzyl)-7-{(1R)-1-[(1S)-1-hydroxyethyl]-4-phenylbutyl}-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

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