Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 1-ethyl 2-(phenylmethyl) ester, (1S,3aR,6aS)-

Base Information

Chemical Name:Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 1-ethyl 2-(phenylmethyl) ester, (1S,3aR,6aS)-
CAS No.:402958-24-1
Molecular Formula:C18H23NO4
Molecular Weight:317.385
Hs Code.:
Mol file:402958-24-1.mol

Synonyms:Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid,hexahydro-,1-ethyl-2-(phenylmethyl) ester,(1R,3aS,6aR);CYC022;

Suppliers and Price of Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 1-ethyl 2-(phenylmethyl) ester, (1S,3aR,6aS)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 1-ethyl 2-(phenylmethyl) ester, (1S,3aR,6aS)-

Chemical Property:

PSA：55.84000
LogP:2.92470

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 1-ethyl 2-(phenylmethyl) ester, (1S,3aR,6aS)-

There total 10 articles about Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 1-ethyl 2-(phenylmethyl) ester, (1S,3aR,6aS)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 402958-23-0
(1S,3aR,6aS)-4-Methylsulfanylthiocarboxyoxy-hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-ethyl ester

: 402958-24-1,864185-80-8
(1S,3aR,6aS)-Hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-ethyl ester

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 95 ℃; for 1h;

Reference yield:

: C₂₄H₂₉N₃O₆S

: 402958-24-1,864185-80-8
(1S,3aR,6aS)-Hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-ethyl ester

Guidance literature:: With sodium ethanolate; In ethanol; for 5h; Reflux;

Reference yield:

: 402958-21-8,158340-62-6
(1S,3aR,6aS)-4-Oxo-hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-ethyl ester

: 402958-24-1,864185-80-8
(1S,3aR,6aS)-Hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: NaBH₄ / ethanol

2: NaH / tetrahydrofuran

3: n-Bu₃SnH; AIBN / toluene

With sodium tetrahydroborate; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; sodium hydride; In tetrahydrofuran; ethanol; toluene; 3: Barton deoxygenation;
DOI:10.1016/j.bmcl.2003.09.074