(2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE

Base Information

Chemical Name:(2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE
CAS No.:906559-60-2
Molecular Formula:C₁₂H₂₄N₂O₂
Molecular Weight:228.335
Hs Code.:2933599090
Mol file:906559-60-2.mol

Synonyms:(2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE;(2S,5R)-tert-butyl 2-ethyl-5-Methylpiperazine-1-carboxylate;(2S,5R)-2-Ethyl-5-methyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester

Suppliers and Price of (2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2S,5R)-tert-Butyl5-ethyl-2-methylpiperazine-1-carboxylate 95+%
1g
$ 772.00

Chemenu
tert-butyl(2S,5R)-5-ethyl-2-methylpiperazine-1-carboxylate 95%
1g
$ 729.00

American Custom Chemicals Corporation
(2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE 95.00%
1G
$ 353.85

Alichem
(2S,5R)-tert-Butyl5-ethyl-2-methylpiperazine-1-carboxylate
1g
$ 653.12

ACHEMBLOCK
(2S,5R)-tert-Butyl2-ethyl-5-methylpiperazine-1-carboxylate 95%
5G
$ 2980.00

Total 15 raw suppliers

Chemical Property of (2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Boiling Point:297.443°C at 760 mmHg
PKA:8.55±0.60(Predicted)
Flash Point:133.689°C
PSA：41.57000
Density:0.958g/cm³
LogP:2.26050
Storage Temp.:2-8°C

Purity/Quality:

99% ^*data from raw suppliers

(2S,5R)-tert-Butyl5-ethyl-2-methylpiperazine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE

There total 1 articles about (2S,5R)-2-ETHYL-5-METHYL-N-BOC-PIPERAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 906810-51-3
(2S,5R)-1-tert-butoxycarbonyl-2-ethyl-5-methylpiperazine acetate

: 906559-60-2
(2S,5R)-1-boc-2-ethyl-5-methyl-piperazine

Guidance literature:: With triethylamine; In dichloromethane;

Reference yield:

: 906559-60-2
(2S,5R)-1-boc-2-ethyl-5-methyl-piperazine

: C₂₅⁽¹⁴⁾CH₃₄ClN₅O₃

Guidance literature:: Multi-step reaction with 7 steps

1: 16 h

2: hydrogenchloride; water / 1 h

3: sodium tris(acetoxy)borohydride; sodium sulfate / tetrahydrofuran

4: hydrogenchloride / water / 1 h

5: dmap; triethylamine / acetonitrile

6: piperidine / tetrahydrofuran / 1 h

7: tetrabutyl ammonium fluoride

With piperidine; hydrogenchloride; dmap; tetrabutyl ammonium fluoride; water; sodium tris(acetoxy)borohydride; sodium sulfate; triethylamine; In tetrahydrofuran; water; acetonitrile;
DOI:10.1002/jlcr.1773

Reference yield:

: 906559-60-2
(2S,5R)-1-boc-2-ethyl-5-methyl-piperazine

: C₂₄⁽¹⁴⁾CH₃₄ClN₇O₂

Guidance literature:: Multi-step reaction with 8 steps

1: 16 h

2: hydrogenchloride; water / 1 h

3: sodium tris(acetoxy)borohydride; sodium sulfate / tetrahydrofuran

4: hydrogenchloride / water / 1 h

5: dmap; triethylamine / acetonitrile

6: piperidine / tetrahydrofuran / 1 h

7: tetrabutyl ammonium fluoride

8: hydrazine hydrate / methanol / 65 °C

With piperidine; hydrogenchloride; dmap; tetrabutyl ammonium fluoride; water; sodium tris(acetoxy)borohydride; hydrazine hydrate; sodium sulfate; triethylamine; In tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1002/jlcr.1773