3AR,5R,6S,7R,7AR-5-Hydroxymethyl-2-methyl-5,6,7,7A-tetrahydro-3AH-pyrano[3,2-D]thiazole-6,7-diol

Base Information Edit

Chemical Name:3AR,5R,6S,7R,7AR-5-Hydroxymethyl-2-methyl-5,6,7,7A-tetrahydro-3AH-pyrano[3,2-D]thiazole-6,7-diol
CAS No.:179030-22-9
Molecular Formula:C8H13NO4S
Molecular Weight:219.262
Hs Code.:
UNII:ML5FHL557A
Nikkaji Number:J760.469F
Wikidata:Q27284100
Pharos Ligand ID:MBRKC1KZKW64
Metabolomics Workbench ID:148238
ChEMBL ID:CHEMBL257158
Mol file:179030-22-9.mol

Synonyms:N-acetyl-glucosamine thiazoline;N-acetylglucosamine thiazoline;NAG-thiazoline

Suppliers and Price of 3AR,5R,6S,7R,7AR-5-Hydroxymethyl-2-methyl-5,6,7,7A-tetrahydro-3AH-pyrano[3,2-D]thiazole-6,7-diol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol
25mg
$ 445.00

TRC
3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol
5mg
$ 130.00

TRC
3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol
50mg
$ 835.00

Medical Isotopes, Inc.
3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol
500 mg
$ 2200.00

Chemenu
(3aR,5R,6S,7R,7aR)-5-(Hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazole-6,7-diol 95%
1g
$ 632.00

Biosynth Carbosynth
N-Acetyl-glucosaminyl thiazoline
10 mg
$ 100.00

Biosynth Carbosynth
N-Acetyl-glucosaminyl thiazoline
5 mg
$ 65.00

Biosynth Carbosynth
N-Acetyl-glucosaminyl thiazoline
50 mg
$ 300.00

Biosynth Carbosynth
N-Acetyl-glucosaminyl thiazoline
100 mg
$ 550.00

Biosynth Carbosynth
N-Acetyl-glucosaminyl thiazoline
25 mg
$ 165.00

Total 12 raw suppliers

Chemical Property of 3AR,5R,6S,7R,7AR-5-Hydroxymethyl-2-methyl-5,6,7,7A-tetrahydro-3AH-pyrano[3,2-D]thiazole-6,7-diol Edit

Chemical Property:

Boiling Point:443.0±45.0 °C(Predicted)
PKA:13.16±0.70(Predicted)
PSA：107.58000
Density:1.81±0.1 g/cm3(Predicted)
LogP:-1.60520
Storage Temp.:Hygroscopic, Refrigerator, Under inert atmosphere
Solubility.:Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:-1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:219.05652907
Heavy Atom Count:14
Complexity:260

Purity/Quality:

97% ^*data from raw suppliers

3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2C(C(C(OC2S1)CO)O)O
Isomeric SMILES:CC1=N[C@@H]2[C@H]([C@@H]([C@H](O[C@@H]2S1)CO)O)O
Uses 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol, can be used in the synthesis of Hexosaminidase inhibitors, which are the new drug candidates for the therapy of osteoarthritis.

Technology Process of 3AR,5R,6S,7R,7AR-5-Hydroxymethyl-2-methyl-5,6,7,7A-tetrahydro-3AH-pyrano[3,2-D]thiazole-6,7-diol

There total 4 articles about 3AR,5R,6S,7R,7AR-5-Hydroxymethyl-2-methyl-5,6,7,7A-tetrahydro-3AH-pyrano[3,2-D]thiazole-6,7-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%